Evidence map›Paper›PMID 33451988›Full record

ArticleImmunoHorizons2021

Uremia Coupled with Mucosal Damage Predisposes Mice with Kidney Disease to Systemic Infection by Commensal

Chetan V Jawale, De-Dong Li, Kritika Ramani, Li Lin, Kelvin Li, Barbara Methe, Partha Sarathi Biswas

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Study on Nursing Effect of Psychological Intervention on Uremic Hemodialysis Patients.Computational and mathematical methods in medicine · 2022
    Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chetan V JawaleDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261; and.
De-Dong LiDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261; and.ORCID 0000-0002-9474-390X
Kritika RamaniDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261; and.
Li LinDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261; and.
Kelvin LiDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.ORCID 0000-0003-3922-5664
Barbara MetheDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15261.
Partha Sarathi BiswasDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261; and psb13@pitt.edu.
University of Pittsburgh · US

Funding

Mechanisms of neutrophil dysfunction in antifungal immunityR01AI142354 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BISWAS, PARTHA SARATHI, NOLIN, THOMAS DOUGLAS · 2019 to 2023
$2.4M
Mechanisms of IL-17 Mediated Host Defense in the KidneyR01DK104680 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BISWAS, PARTHA SARATHI · 2015 to 2019
$1.5M
Regulation of IL-17 signaling by RNA binding proteins in kidney diseasesR21AI145242 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BISWAS, PARTHA SARATHI, GAFFEN, SARAH L · 2019 to 2020
$424k
NIAID NIH HHS R01 AI142354NIAID NIH HHS R21 AI145242NIDDK NIH HHS R01 DK104680
6 · The paper itself

Abstract

Infections are the second major cause of mortality in patients with kidney disease and accompanying uremia. Both vascular access and non-access-related infections contribute equally to the infection-related deaths in patients with kidney disease. Dialysis is the most common cause of systemic infection by

Indexed as

AnimalsCandida albicansCitrobacter rodentiumDisease Models, AnimalDisease SusceptibilityHost-Pathogen InteractionsHumansIntestinal MucosaIntestinesMiceMice, Inbred C57BLSymbiosisUremia

Identifiers

PMID33451988
PMCPMC7913778
OpenAlexW3121076218

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.