ArticleRespiratory research2021
The product of trunk muscle area and density on the CT image is a good indicator of energy expenditure in patients with or at risk for COPD.
Article in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Computed tomography-based body composition measures in COPD and their association with clinical outcomes: A systematic review.Chronic respiratory diseasePooled it
- Impact of Erector Spinae Muscle Mass on Recovery From Tube Feeding in Older Patients With Dysphagia.Geriatrics & gerontology international · 2026Article
- Prognostic Value of Chest CT-Derived Pectoralis Muscle Metrics for In-Hospital Mortality and Invasive Mechanical Ventilation in AECOPD.International journal of chronic obstructive pulmonary disease · 2026Article
- The cross-sectional area of the pectoralis major muscle and future exacerbations in patients presenting with bronchiectasis exacerbation: a prospective observational study.BMC pulmonary medicine · 2025Observational
- The cross-sectional area of the erector spinae muscle is an adverse indicator for patient with acute exacerbation of chronic obstructive pulmonary disease.Scientific reports · 2025Article
- Medical nutrition therapy in chronic obstructive pulmonary disease: A narrative review.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025Review
- Antigravity muscle density on computed tomography and health-related independence in normal weight patients with chronic obstructive pulmonary disease.Respiratory research · 2025Article
- Quantitative CT evaluation of extrapulmonary lesions in chronic obstructive pulmonary disease: a narrative review.Journal of thoracic disease · 2025Review
- Effect of Common Medications on Longitudinal Pectoralis Muscle Area in Smokers.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025Article
- Effect of osteosarcopenia on feeding status in hospitalized patients with suspected dysphagia.PloS one · 2024Article
- Article
- The role of diet and nutrition in the management of COPD.European respiratory review : an official journal of the European Respiratory Society · 2023Review
- Urinary titin N-fragment as a predictor of decreased skeletal muscle mass in patients with interstitial lung diseases.Scientific reports · 2023Article
- 30 s sit-to-stand power is positively associated with chest muscle thickness in COVID-19 survivors.Chronic respiratory diseaseArticle
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Authors and funding
14 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundPhysical inactivity due to cachexia and muscle wasting is well recognized as a sign of poor prognosis in chronic obstructive pulmonary disease (COPD). However, there have been no reports on the relationship between trunk muscle measurements and energy expenditure parameters, such as the total energy expenditure (TEE) and physical activity level (PAL), in COPD. In this study, we investigated the associations of computed tomography (CT)-derived muscle area and density measurements with clinical parameters, including TEE and PAL, in patients with or at risk for COPD, and examined whether these muscle measurements serve as an indicator of TEE and PAL.
methodsThe study population consisted of 36 male patients with (n = 28, stage 1-4) and at risk for (n = 8) COPD aged over 50 years. TEE was measured by the doubly labeled water method, and PAL was calculated as the TEE/basal metabolic rate estimated by the indirect method. The cross-sectional areas and densities of the pectoralis muscles, rectus abdominis muscles, and erector spinae muscles were measured. We evaluated the relationship between these muscle measurements and clinical outcomes, including body composition, lung function, muscle strength, TEE, and PAL.
resultsAll the muscle areas were significantly associated with TEE, severity of emphysema, and body composition indices such as body mass index, fat-free mass, and trunk muscle mass. All trunk muscle densities were correlated with PAL. The product of the rectus abdominis muscle area and density showed the highest association with TEE (r = 0.732) and PAL (r = 0.578). Several trunk muscle measurements showed significant correlations with maximal inspiratory and expiratory pressures, indicating their roles in respiration.
conclusionsCT-derived measurements for trunk muscles are helpful in evaluating physical status and function in patients with or at risk for COPD. Particularly, trunk muscle evaluation may be a useful marker reflecting TEE and PAL.
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