Evidence map›Paper›PMID 33451261›Full record

SynthesisAmerican journal of men's health

Assessing Health-Related Quality of Life Among Survivors of Testicular Cancer: A Systematic Review.

Michael J Rovito, Agata Bruzzone, Eunkyung Lee, Humberto López Castillo, Walker Talton, Lindsay Taliaferro, Derek Falk

Abstract readSystematic Review
In one paragraph

Synthesis in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Assessment of the Mental Health of Police Officers: A Systematic Review of Specific Instruments.International journal of environmental research and public health · 2024
    Pooled it
  7. Pooled it
  8. Pooled it
  9. Goal-Focused Emotion-Regulation Therapy (GET) in Young Adult Testicular Cancer Survivors: A Randomized Pilot Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023
    Trial
  10. Review
  11. Review
  12. Article
  13. Article
  14. Exploring online discussions in men with testicular cancer: a qualitative and sentiment analysis of Reddit posts.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  15. Article
  16. Review
  17. Young adult Latino testicular cancer survivors: a pilot study of Goal-focused Emotion regulation Therapy (GET).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  18. Review
  19. Testicular cancer survivorship: Long-term toxicity and management.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael J RovitoDepartment of Health Sciences, University of Central Florida, Orlando, FL, USA.ORCID 0000-0001-8086-3460
Agata BruzzoneDepartment of Health Sciences, University of Central Florida, Orlando, FL, USA.
Eunkyung LeeDepartment of Health Sciences, University of Central Florida, Orlando, FL, USA.
Humberto López CastilloDepartment of Health Sciences, University of Central Florida, Orlando, FL, USA.
Walker TaltonDepartment of Health Sciences, University of Central Florida, Orlando, FL, USA.
Lindsay TaliaferroDepartment of Population Health Sciences, University of Central Florida, Orlando, FL, USA.
Derek FalkDepartment of Social Sciences and Health Policy, Wake Forest University, Winston Salem, NC, USA.

Funding

Cancer Prevention And Control Training Grant (CAPACITY)T32CA122061 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KRISTIE L FOLEY, Kathryn Elizabeth Weaver · 2019 to 2026
$2.1M
NCI NIH HHS T32 CA122061
6 · The paper itself

Abstract

This study aimed to determine if the current health-related quality of life (HRQoL) tools created for survivors of testicular cancer are collecting the highest quality of data via a two-step methodological critique of both the seminal studies that produced a survivor of testicular cancer HRQoL tool (Phase 1) and the actual tool itself (Phase 2). It is the goal of this current article to present and discuss Phase 1.A systematic review aimed to assess the methodological quality of studies conducted to create instruments used to measure survivors of testicular cancer HRQoL. Five reviewers independently assessed each study with the 20-item Appraisal Tool for Cross-Sectional Studies (AXIS). Inter-rater agreement and Fleiss' kappa was also assessed to ensure consistency in reported scores. Assessments for the EORTC QLQ-TC 26 and CAYA-T studies were low (AXIS 52.5%; IRA 95%; κ = 0.779) and fair (AXIS 65%; IRA 80%; κ = 0.599), respectively. Critical appraisal of the scales included issues within the three core AXIS domains. Primary concerns related to sampling methodology and the lack of a qualitative component of their core conceptual development phase.Both reviewed seminal studies have significant methodological concerns that question the tools' quality. Next steps include extensive appraisal of the psychometric properties of the EORTC QLQ TC-26 and the CAYA-T to complete the comprehensive review. Accurate and reliable data are necessary to understand survivor of testicular cancer HRQoL and assist in building the bridge of communication between health care professionals and survivors to help to improve patient outcomes.

Indexed as

Cancer SurvivorsCross-Sectional StudiesHumansMaleQuality of LifeSurveys and QuestionnairesTesticular NeoplasmsAXIScancer survivorshipcritical appraisalquality of lifeTesticular cancer

Identifiers

PMID33451261
PMCPMC7812415

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.