Evidence map›Paper›PMID 33451186›Full record

ArticleIET systems biology2018

Gene expression feature selection for prostate cancer diagnosis using a two-phase heuristic-deterministic search strategy.

Saleh Shahbeig, Akbar Rahideh, Mohammad Sadegh Helfroush, Kamran Kazemi

Abstract read
In one paragraph

Article in IET systems biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Saleh ShahbeigDepartment of Electrical and Electronics Engineering, Shiraz University of Technology, Shiraz, Iran.
Akbar RahidehDepartment of Electrical and Electronics Engineering, Shiraz University of Technology, Shiraz, Iran.
Mohammad Sadegh HelfroushDepartment of Electrical and Electronics Engineering, Shiraz University of Technology, Shiraz, Iran.
Kamran KazemiDepartment of Electrical and Electronics Engineering, Shiraz University of Technology, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, a two-phase search strategy is proposed to identify the biomarkers in gene expression data set for the prostate cancer diagnosis. A statistical filtering method is initially employed to remove the noisiest data. In the first phase of the search strategy, a multi-objective optimisation based on the binary particle swarm optimisation algorithm tuned by a chaotic method is proposed to select the optimal subset of genes with the minimum number of genes and the maximum classification accuracy. Finally, in the second phase of the search strategy, the cache-based modification of the sequential forward floating selection algorithm is used to find the most discriminant genes from the optimal subset of genes selected in the first phase. The results of applying the proposed algorithm on the available challenging prostate cancer data set demonstrate that the proposed algorithm can perfectly identify the informative genes such that the classification accuracy, sensitivity, and specificity of 100% are achieved with only nine biomarkers.

Indexed as

available challenging prostate cancer databiological organsbiomarkerscancerchaotic methoddiscriminant genesfeature extractiongene expression datagene expression feature selectiongeneticsheuristic-deterministic search strategyinformative genesmultiobjective optimisationnoisiest dataoptimisationparticle swarm optimisationparticle swarm optimisation algorithmpattern classificationprostate cancer diagnosissearch problemsselection algorithmstatistical filtering methodtwo-phase search strategy

Identifiers

PMID33451186
PMCPMC8687315

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.