Evidence map›Paper›PMID 33451152›Full record

ArticleMolecules (Basel, Switzerland)2021

Near-Ultraviolet Circular Dichroism and Two-Dimensional Spectroscopy of Polypeptides.

Francesco Segatta, David M Rogers, Naomi T Dyer, Ellen E Guest, Zhuo Li, Hainam Do, Artur Nenov, Marco Garavelli, Jonathan D Hirst

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Structural and functional analysis of a homotrimeric collagen peptide.Frontiers in bioengineering and biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco SegattaDipartimento di Chimica Industriale "Toso Montanari", Universita' degli Studi di Bologna, Viale del Risorgimento, 4, I-40136 Bologna, Italy.ORCID 0000-0003-4150-6676
David M RogersSchool of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.ORCID 0000-0003-2167-113X
Naomi T DyerSchool of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Ellen E GuestSchool of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Zhuo LiSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Hainam DoDepartment of Chemical and Environmental Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.
Artur NenovDipartimento di Chimica Industriale "Toso Montanari", Universita' degli Studi di Bologna, Viale del Risorgimento, 4, I-40136 Bologna, Italy.ORCID 0000-0003-3071-5341
Marco GaravelliDipartimento di Chimica Industriale "Toso Montanari", Universita' degli Studi di Bologna, Viale del Risorgimento, 4, I-40136 Bologna, Italy.ORCID 0000-0002-0796-289X
Jonathan D HirstSchool of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.ORCID 0000-0002-2726-0983

Funding

Engineering and Physical Sciences Research Council EP/R512059/1Royal Academy of Engineering CiET2021\17
6 · The paper itself

Abstract

A fully quantitative theory of the relationship between protein conformation and optical spectroscopy would facilitate deeper insights into biophysical and simulation studies of protein dynamics and folding. In contrast to intense bands in the far-ultraviolet, near-UV bands are much weaker and have been challenging to compute theoretically. We report some advances in the accuracy of calculations in the near-UV, which were realised through the consideration of the vibrational structure of the electronic transitions of aromatic side chains.

Indexed as

Circular DichroismPeptidesProtein ConformationSpectrophotometry, UltravioletPeptidesaromatic chromophorescomputational spectroscopyelectronic structureprotein

Identifiers

PMID33451152
PMCPMC7828623

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.