Evidence map›Paper›PMID 33451135›Full record

ArticleInternational journal of molecular sciences2021

Systematic Identification of Protein Targets of Sub5 Using

Pramod Shah, Chien-Sheng Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Designed Multifunctional Peptides for Intracellular Targets.Antibiotics (Basel, Switzerland) · 2022
    Review
  2. Peptides for Health Benefits 2020.International journal of molecular sciences · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pramod ShahGraduate Institute of Systems Biology and Bioinformatics, and Department of Biomedical Sciences and Engineering, College of Health Sciences and Technology, National Central University, Jhongli 32001, Taiwan.ORCID 0000-0002-7298-2221
Chien-Sheng ChenGraduate Institute of Systems Biology and Bioinformatics, and Department of Biomedical Sciences and Engineering, College of Health Sciences and Technology, National Central University, Jhongli 32001, Taiwan.
National Central University · TW

Funding

Ministry of Science and Technology, Taiwan MOST 108-2320-B-006-038-MY3
6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are intensively studied in terms of alternative drugs. Sub5 is a synthetic 12-mer AMP with substitutions of five amino acids of bactenecin 2A (Bac2A), a linear-ized bactenecin variant of bovine. Sub5 is highly effective against fungi with an ability to trans-locate cell membrane, but its targets are unknown. Systematic analysis of Sub5 targets will facil-itate our understanding on its mechanism of action. In this study, we used high-throughput

Indexed as

ProteomeProteomicsAmino Acid MotifsAntimicrobial Cationic PeptidesCarrier ProteinsComputational BiologyGene OntologyMolecular Sequence AnnotationProtein BindingProtein Interaction Domains and MotifsProtein Interaction MappingProtein Interaction MapsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAntimicrobial Cationic PeptidesCarrier ProteinsProteomeSaccharomyces cerevisiae Proteinsantifungal activityantimicrobial peptides (AMPs)proteome microarraySub5target identification

Identifiers

PMID33451135
PMCPMC7828587
OpenAlexW3118284013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.