Evidence map›Paper›PMID 33451125›Full record

ArticleViruses2021

Surveillance and Genetic Characterization of Virulent Newcastle Disease Virus Subgenotype V.3 in Indigenous Chickens from Backyard Poultry Farms and Live Bird Markets in Kenya.

Henry M Kariithi, Helena L Ferreira, Catharine N Welch, Leonard O Ateya, Auleria A Apopo, Richard Zoller, Jeremy D Volkening, Dawn Williams-Coplin, Darren J Parris, Tim L Olivier and 5 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 3 countries.

Henry M KariithiExotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA.ORCID 0000-0002-9250-9108
Helena L FerreiraExotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA.
Catharine N WelchFlorida Department of Environmental Protection, Division of Recreation and Parks 33104 NW 192nd Ave, Okeechobee, FL 34972, USA.
Leonard O AteyaBiotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kaptagat Road, Loresho, Nairobi P.O. Box 57811-00200, Kenya.
Auleria A ApopoDirectorate of Veterinary Services, State Department for Livestock, Ministry of Agriculture, Livestock, Fisheries and Cooperatives, Nairobi P.O. Box 34188-00100, Kenya.
Richard ZollerExotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA.
Jeremy D VolkeningBASE2BIO, Oshkosh, WI 54904, USA.ORCID 0000-0002-8892-7155
Dawn Williams-CoplinExotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA.
Darren J ParrisExotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA.
Tim L OlivierExotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA.
Dana GoldenbergExotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA.
Yatinder S BinepalBiotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kaptagat Road, Loresho, Nairobi P.O. Box 57811-00200, Kenya.
Sonia M HernandezWarnell School of Forestry and Natural Resources and The Southeastern Cooperative Wildlife Disease Study at the College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Claudio L AfonsoBASE2BIO, Oshkosh, WI 54904, USA.ORCID 0000-0001-5699-4743
David L SuarezExotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA.ORCID 0000-0003-4582-6116
U.S. National Poultry Research Center · USKenya Agricultural and Livestock Research Organization · KEOshkosh (United States) · USFlorida Department of Environmental Protection · USMinistry of Agriculture Livestock and Fisheries · KEUniversidade de São Paulo · BRUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kenyan poultry consists of ~80% free-range indigenous chickens kept in small flocks (~30 birds) on backyard poultry farms (BPFs) and they are traded via live bird markets (LBMs). Newcastle disease virus (NDV) was detected in samples collected from chickens, wild farm birds, and other domestic poultry species during a 2017-2018 survey conducted at 66 BPFs and 21 LBMs in nine Kenyan counties. NDV nucleic acids were detected by rRT-PCR L-test in 39.5% (641/1621) of 1621 analyzed samples, of which 9.67% (62/641) were NDV-positive by both the L-test and a fusion-test designed to identify the virulent virus, with a majority being at LBMs (64.5%; 40/62) compared to BPFs (25.5%; 22/62). Virus isolation and next-generation sequencing (NGS) on a subset of samples resulted in 32 complete NDV genome sequences with 95.8-100% nucleotide identities amongst themselves and 95.7-98.2% identity with other east African isolates from 2010-2016. These isolates were classified as a new sub-genotype, V.3, and shared 86.5-88.9% and 88.5-91.8% nucleotide identities with subgenotypes V.1 and V.2 viruses, respectively. The putative fusion protein cleavage site (

Indexed as

GenotypeAnimalsChickensFarmsGenome, ViralGenomicsKenyaMolecular EpidemiologyNewcastle DiseaseNewcastle disease virusPhylogenyPhylogeographyPoultry DiseasesPublic Health SurveillanceRNA, ViralSpatio-Temporal AnalysisRNA, ViralcloacalNewcastle diseaseoropharyngealphylogeographyspatial-temporal dispersal

Identifiers

PMID33451125
PMCPMC7828601
OpenAlexW3118554878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.