Evidence map›Paper›PMID 33451058›Full record

ArticleBiomedicines2021

Rational Design of Albumin Theranostic Conjugates for Gold Nanoparticles Anticancer Drugs: Where the Seed Meets the Soil?

Tatyana V Popova, Inna A Pyshnaya, Olga D Zakharova, Andrey E Akulov, Oleg B Shevelev, Julia Poletaeva, Evgenii L Zavjalov, Vladimir N Silnikov, Elena I Ryabchikova, Tatyana S Godovikova

Abstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Quantification ofMedicinal research reviews · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Design of the NewMolecules (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tatyana V PopovaInstitute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Lavrentiev ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0002-1098-8628
Inna A PyshnayaInstitute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Lavrentiev ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0002-7559-2376
Olga D ZakharovaInstitute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Lavrentiev ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0002-2054-561X
Andrey E AkulovInstitute of Cytology and Genetics, SB RAS, Lavrentiev ave. 10, 630090 Novosibirsk, Russia.
Oleg B ShevelevInstitute of Cytology and Genetics, SB RAS, Lavrentiev ave. 10, 630090 Novosibirsk, Russia.ORCID 0000-0003-3200-958X
Julia PoletaevaInstitute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Lavrentiev ave. 8, 630090 Novosibirsk, Russia.
Evgenii L ZavjalovInstitute of Cytology and Genetics, SB RAS, Lavrentiev ave. 10, 630090 Novosibirsk, Russia.
Vladimir N SilnikovInstitute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Lavrentiev ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0002-7100-8953
Elena I RyabchikovaInstitute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Lavrentiev ave. 8, 630090 Novosibirsk, Russia.ORCID 0000-0003-4714-1524
Tatyana S GodovikovaInstitute of Chemical Biology and Fundamental Medicine, The Siberian Branch of the Russian Academy of Sciences, Lavrentiev ave. 8, 630090 Novosibirsk, Russia.

Funding

Russian Science Foundation №19-74-20123
6 · The paper itself

Abstract

Multifunctional gold nanoparticles (AuNPs) may serve as a scaffold to integrate diagnostic and therapeutic functions into one theranostic system, thereby simultaneously facilitating diagnosis and therapy and monitoring therapeutic responses. Herein, albumin-AuNP theranostic agents have been obtained by conjugation of an anticancer nucleotide trifluorothymidine (TFT) or a boron-neutron capture therapy drug undecahydro-

Indexed as

albumin theranostic conjugatesboronated albumin conjugatefluorescence-based molecular imaginggold nanoparticlestrifluorothymidine-albumin conjugate

Identifiers

PMID33451058
PMCPMC7828547

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.