Evidence map›Paper›PMID 33451043›Full record

ArticleInternational journal of molecular sciences2021

Systemic Inflammation and the Breakdown of Intestinal Homeostasis Are Key Events in Chronic Spinal Cord Injury Patients.

David Diaz, Elisa Lopez-Dolado, Sergio Haro, Jorge Monserrat, Carlos Martinez-Alonso, Dimitrios Balomeros, Agustín Albillos, Melchor Alvarez-Mon

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  18. Inflammation in Health and Disease: New Insights and Therapeutic Avenues.International journal of molecular sciences · 2022
    Article
  19. Spinal Cord Injury Impairs Lung Immunity in Mice.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

David DiazDepartment of Medicine, University of Alcalá, Crta N-II km 33.6, Alcalá de Henares, 28871 Madrid, Spain.
Elisa Lopez-DoladoDepartment of Medicine, University of Alcalá, Crta N-II km 33.6, Alcalá de Henares, 28871 Madrid, Spain.ORCID 0000-0002-3358-727X
Sergio HaroDepartment of Medicine, University of Alcalá, Crta N-II km 33.6, Alcalá de Henares, 28871 Madrid, Spain.
Jorge MonserratDepartment of Medicine, University of Alcalá, Crta N-II km 33.6, Alcalá de Henares, 28871 Madrid, Spain.ORCID 0000-0003-1775-4645
Carlos Martinez-AlonsoDepartment of Immunology and Oncology, Universidad Autónoma de Madrid, Calle Darwin, 3, 28049 Madrid, Spain.
Dimitrios BalomerosDepartment of Immunology and Oncology, Universidad Autónoma de Madrid, Calle Darwin, 3, 28049 Madrid, Spain.
Agustín AlbillosDepartment of Medicine, University of Alcalá, Crta N-II km 33.6, Alcalá de Henares, 28871 Madrid, Spain.
Melchor Alvarez-MonDepartment of Medicine, University of Alcalá, Crta N-II km 33.6, Alcalá de Henares, 28871 Madrid, Spain.
Universidad de Alcalá · ESUniversidad Autónoma de Madrid · ES

Funding

Fondo de Investigación de la Seguridad Social FIS PI-14/01935Spanish Ministerio de Ciencia y Tecnología, Instituto de Salud Carlos III PI051871Spanish Ministerio de Economía y Competitividad B2017/BMD-3804
6 · The paper itself

Abstract

Our aim was to investigate the subset distribution and function of circulating monocytes, proinflammatory cytokine levels, gut barrier damage, and bacterial translocation in chronic spinal cord injury (SCI) patients. Thus, 56 SCI patients and 28 healthy donors were studied. The levels of circulating CD14

Indexed as

Disease SusceptibilityAdultBiomarkersCase-Control StudiesChronic DiseaseCytokinesFemaleHomeostasisHumansInflammationInflammation MediatorsIntestinal DiseasesMaleMonocytesPhagocytesPhagocytosisBiomarkersCytokinesInflammation MediatorsTumor Necrosis Factor-alphabacterial translocationchronic spinal cord injurycytokinesgut barrier damagemonocytesystemic inflammation

Identifiers

PMID33451043
PMCPMC7828526
OpenAlexW3120072604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.