Evidence map›Paper›PMID 33450876›Full record

ArticleToxins2021

Investigating Multi-Mycotoxin Exposure in Occupational Settings: A Biomonitoring and Airborne Measurement Approach.

Sophie Ndaw, Daniele Jargot, Guillaume Antoine, Flavien Denis, Sandrine Melin, Alain Robert

Abstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Aflatoxin MToxins · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sophie NdawToxicology and Biomonitoring Department, INRS-French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases, 54500 Vandoeuvre-Lés-Nancy, France.ORCID 0000-0002-7518-2465
Daniele JargotPollutant Metrology Department, INRS-French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases, 54500 Vandoeuvre-Lés-Nancy, France.
Guillaume AntoineToxicology and Biomonitoring Department, INRS-French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases, 54500 Vandoeuvre-Lés-Nancy, France.
Flavien DenisToxicology and Biomonitoring Department, INRS-French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases, 54500 Vandoeuvre-Lés-Nancy, France.
Sandrine MelinPollutant Metrology Department, INRS-French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases, 54500 Vandoeuvre-Lés-Nancy, France.
Alain RobertToxicology and Biomonitoring Department, INRS-French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases, 54500 Vandoeuvre-Lés-Nancy, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Investigating workplace exposure to mycotoxins is of the utmost importance in supporting the implementation of preventive measures for workers. The aim of this study was to provide tools for measuring mycotoxins in urine and airborne samples. A multi-class mycotoxin method was developed in urine for the determination of aflatoxin B1, aflatoxin M1, ochratoxin A, ochratoxin α, deoxynivalenol, zearalenone, α-zearalenol, β-zearalenol, fumonisin B1, HT2-toxin and T2-toxin. Analysis was based on liquid chromatography-high resolution mass spectrometry. Sample pre-treatments included enzymatic digestion and an online or offline sample clean-up step. The method was validated according to the European Medicines Agency guidance procedures. In order to estimate external exposure, air samples collected with a CIP 10 (Capteur Individuel de Particules 10) personal dust sampler were analyzed for the quantification of up to ten mycotoxins, including aflatoxins, ochratoxin A, deoxynivalenol, zearalenone, fumonisin B1 and HT-2 toxin and T-2 toxin. The method was validated according to standards for workplace exposure to chemical and biological agents EN 482. Both methods, biomonitoring and airborne mycotoxin measurement, showed good analytical performances. They were successfully applied in a small pilot study to assess mycotoxin contamination in workers during cleaning of a grain elevator. We demonstrated that this approach was suitable for investigating occupational exposure to mycotoxins.

Indexed as

Air PollutantsBiological MonitoringChromatography, LiquidHumansMycotoxinsOccupational ExposureOccupational HealthPilot ProjectsSpectrometry, Mass, Electrospray IonizationTandem Mass SpectrometryUrineAir PollutantsMycotoxinsairbiomonitoringdustexposure assessmentHR-MS/MSmycotoxinsoccupational exposure

Identifiers

PMID33450876
PMCPMC7828332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.