Evidence map›Paper›PMID 33450071›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2021

Predictive Value of DXA Appendicular Lean Mass for Incident Fractures, Falls, and Mortality, Independent of Prior Falls, FRAX, and BMD: Findings from the Women's Health Initiative (WHI).

Nicholas C Harvey, John A Kanis, Enwu Liu, Cyrus Cooper, Mattias Lorentzon, Jennifer W Bea, Laura Carbone, Elizabeth M Cespedes Feliciano, Deepika R Laddu, Peter F Schnatz and 6 more

Abstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Sarcopenia Definitions as Predictors of Fracture Risk Independent of FRAXJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021
    Pooled it
  3. Article
  4. Examining the relationship between D3Cr muscle mass, physical performance, and functional limitation in postmenopausal women.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
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  11. Sarcopenia definitions and their association with injurious falls in older Swedish women from the Sahlgrenska University Hospital Prospective Evaluation of Risk of Bone fractures (SUPERB) study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
  12. Sarcopenia definitions and their association with fracture risk in older Swedish women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  13. Article
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  16. Interactions Between HR-pQCT Bone Density and DJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Article
  17. Article
  18. Menopause-Related Changes in Body Composition Are Associated With Subsequent Bone Mineral Density and Fractures: Study of Women's Health Across the Nation.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Nicholas C HarveyMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.ORCID 0000-0002-8194-2512
John A KanisCentre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.
Enwu LiuMary McKillop Institute for Health Research, Australian Catholic University, Melbourne, Australia.
Cyrus CooperMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.ORCID 0000-0003-3510-0709
Mattias LorentzonMary McKillop Institute for Health Research, Australian Catholic University, Melbourne, Australia.ORCID 0000-0003-0749-1431
Jennifer W BeaUniversity of Arizona Cancer Center, Tucson, AZ, USA.ORCID 0000-0002-9868-1574
Laura CarboneDepartment of Medicine, Division of Rheumatology, J Harold Harrison, MD, Distinguished University Chair in Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, USA.ORCID 0000-0003-1007-5949
Elizabeth M Cespedes FelicianoDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.ORCID 0000-0003-1192-4017
Deepika R LadduDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Peter F SchnatzReading Hospital / Tower Health, Reading, PA, USA.
Aladdin H ShadyabUniversity of California, San Diego, CA, USA.
Marcia L StefanickDepartment of Medicine (Stanford Prevention Research Center), Stanford School of Medicine, Stanford University, Stanford, CA, USA.
Jean Wactawski-WendeUniversity at Buffalo, the State University of New York, Buffalo, NY, USA.ORCID 0000-0003-3096-9595
Carolyn J CrandallDavid Geffen School of Medicine at the University of California, Los Angeles, CA, USA.ORCID 0000-0001-9441-0198
Helena JohanssonCentre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.
Eugene McCloskeyCentre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.

Funding

The impact of a resistance training intervention on blood pressure control in older adults with SarcopeniaK01HL148503 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LADDU, DEEPIKA · 2019 to 2023
$901k
Medical Research Council 4050502589Medical Research Council G0400491Medical Research Council MC_PC_21003Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2Medical Research Council MR/P020941/1NHLBI NIH HHS HHSN268201600001CNHLBI NIH HHS HHSN268201600002CNHLBI NIH HHS HHSN268201600003CNHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS HHSN268201600018CNHLBI NIH HHS K01 HL148503NIH HHS HHSN26820160Versus Arthritis 17702Versus Arthritis 21231
6 · The paper itself

Abstract

In the Women's Health Initiative (WHI), we investigated associations between baseline dual-energy X-ray absorptiometry (DXA) appendicular lean mass (ALM) and risk of incident fractures, falls, and mortality (separately for each outcome) among older postmenopausal women, accounting for bone mineral density (BMD), prior falls, and Fracture Risk Assessment Tool (FRAX

Indexed as

Hip FracturesOsteoporotic FracturesAbsorptiometry, PhotonAccidental FallsAgedBone DensityFemaleHumansMaleMiddle AgedProspective StudiesRisk AssessmentRisk FactorsWomen's HealthAPPENDICULAR LEAN MASSBMDDXAFRACTUREFRAXOSTEOPOROSIS: EPIDEMIOLOGY

Identifiers

PMID33450071
PMCPMC7610603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.