Evidence map›Paper›PMID 33449646›Full record

ArticleACS biomaterials science & engineering2020

Periosteum Mimetic Coating on Structural Bone Allografts

Zhou Zhuang, Johnson V John, Haofu Liao, Jiebo Luo, Paul Rubery, Addisu Mesfin, Sunil Kumar Boda, Jingwei Xie, Xinping Zhang

Open access · greenAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhou ZhuangCenter for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14621, United States.
Johnson V JohnDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska, Omaha, Nebraska 68198, United States.
Haofu LiaoDepartment of Computer Science, University of Rochester, Rochester, New York 14627, United States.
Jiebo LuoDepartment of Computer Science, University of Rochester, Rochester, New York 14627, United States.
Paul RuberyCenter for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, United States.
Addisu MesfinCenter for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, United States.
Sunil Kumar BodaDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska, Omaha, Nebraska 68198, United States.
Jingwei XieDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska, Omaha, Nebraska 68198, United States.ORCID 0000-0002-8126-1397
Xinping ZhangCenter for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, United States.ORCID 0000-0002-4429-638X
University of Rochester · USUniversity of Nebraska at Omaha · US

Funding

Rochester Resource-Based Center for Bone, Muscle and Orthopaedic Research (ROCSTARR) (Overall Application)P30AR069655 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2016 to 2026
$7.8M
PTH Effects of Craniofacial AllograftsR01DE019902 · NIDCR · UNIVERSITY OF ROCHESTER · PI GAZIT, DAN, SCHWARZ, EDWARD M. · 2009 to 2019
$5.0M
The University of Rochester Core Center for Musculoskeletal Biology and MedicineP30AR061307 · NIAMS · UNIVERSITY OF ROCHESTER · PI SCHWARZ, EDWARD M. · 2011 to 2015
$3.0M
Micro- and nanofiber enabled biomimetic periosteum for bone repair and reconstructionR01AR067859 · NIAMS · UNIVERSITY OF ROCHESTER · PI WANG, HONGJUN, ZHANG, XINPING · 2016 to 2020
$2.7M
Endothelial cell specification at the osteogenic and angiogenic interface in cranial bone tissue engineeringR01DE029790 · NIDCR · UNIVERSITY OF ROCHESTER · PI ZHANG, XINPING · 2020 to 2025
$2.7M
Understanding revascularization and repair of cranial bone grafts via intravital imagingR21DE026256 · NIDCR · UNIVERSITY OF ROCHESTER · PI BROWN, EDWARD BERNARD, ZHANG, XINPING · 2016 to 2017
$435k
Engineering structural bone allografts for enhanced repair and reconstructionR21AR076056 · NIAMS · UNIVERSITY OF ROCHESTER · PI XIE, JINGWEI, ZHANG, XINPING · 2020 to 2021
$365k
NIAMS NIH HHS P30 AR061307NIAMS NIH HHS P30 AR069655NIAMS NIH HHS R01 AR067859NIAMS NIH HHS R21 AR076056NIDCR NIH HHS R01 DE019902NIDCR NIH HHS R01 DE029790NIDCR NIH HHS R21 DE026256
6 · The paper itself

Abstract

Structural bone allograft transplantation remains one of the common strategies for repair and reconstruction of large bone defects. Due to the loss of periosteum that covers the outer surface of the cortical bone, the healing and incorporation of allografts is extremely slow and limited. To enhance the biological performance of allografts, herein, we report a novel and simple approach for engineering a periosteum mimetic coating on the surface of structural bone allografts

Indexed as

Mesenchymal Stem CellsPeriosteumAllograftsAnimalsBone TransplantationMiceTissue EngineeringBMP-2 peptidebone allograftperiosteum mimeticpolymer-mediated electrospray depositionsurface coating

Identifiers

PMID33449646
PMCPMC8315206
OpenAlexW3094373855

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.