Evidence map›Paper›PMID 33449611›Full record

ReviewTransplantation2021

Vigilance for Medical Products of Human Origin-Progress on the Notify Library's Global Effort to Share Information and Learning.

Evangelia Petrisli, Claudia Carella, Aurora Navarro, Deirdre Fehily, Douglas Michael Strong, Massimo Cardillo, on behalf of the Notify Editorial Board

Abstract readReview
In one paragraph

Review in Transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Evangelia PetrisliOperative Unit of Microbiology and Virology, Department of Specialized, Experimental, and Diagnostic Medicine, IRCCS St Orsola-Malpighi Polyclinic, University of Bologna, Bologna, Italy.
Claudia CarellaNational Transplant Centre, Istituto Superiore di Sanità, Rome, Italy.
Aurora NavarroDepartment of Biovigilance, Catalan Transplant Organization, Health Department, Generalitat of Catalonia, Barcelona, Spain.
Deirdre FehilyNational Transplant Centre, Istituto Superiore di Sanità, Rome, Italy.
Douglas Michael StrongDepartment of Orthopaedics and Sports Medicine, University of Washington School of Medicine, Seattle, WA.
Massimo CardilloNational Transplant Centre, Istituto Superiore di Sanità, Rome, Italy.
on behalf of the Notify Editorial Board

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWorld Health Assembly Resolution 63.22 mandated World Health Organization to facilitate Member State access to appropriate information on medical products of human origin (MPHO), including collecting data on serious adverse events and reactions. To meet this challenge, the Italian National Transplant Center, with a mandate from World Health Organization, has built and maintained an open-access searchable database of instructive records on disease transmission and other MPHO adverse occurrences.

methodsOne record in the Notify Library describes a specific type of adverse occurrence in 1 type of MPHO and might be linked with 1 or multiple different references. The record inclusion criteria are that it has been reliably documented in a published article or official vigilance reporting system and that it has instructive value for the fields of transfusion, transplantation, or assisted reproduction. The selection and review of references for publication is performed by international experts who collaborate in 5 topic-specific editorial groups: infection transmission, malignancy transmission, living-donor reactions, process-related incidents, and clinical complications. New relevant references are identified through systematic searches and proactive communication by the experts.

resultsThe Library contains 1733 records, quoting 2632 references. Of the records, 41.8% are related to organs, 20.8% to blood and blood components, 16.5% to hematopoietic progenitor cells, 15.2% to tissues, 4.2% to reproductive tissues and cells, and 1.5% to other MPHO.

conclusionsNotify Library is the first open-access, searchable database of systematically identified reports of disease transmission and other adverse occurrences arising from the donation and clinical application of MPHO.

Indexed as

Access to InformationInformation DisseminationProduct Surveillance, PostmarketingWorld Health OrganizationAnimalsBiological ProductsBiological TherapyHumansPatient SafetyRisk AssessmentRisk FactorsBiological Products

Identifiers

PMID33449611
PMCPMC8376274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.