ArticlePain2021
Composite outcomes for pain clinical trials: considerations for design and interpretation.
Article in Pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06531317 (Machine-Learning Based EEG Biomarkers for Personalized Interventions), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Machine-Learning Based EEG Biomarkers for Personalized Interventions
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Personalized outcomes in neuropathic pain: a clinical relevance and assay sensitivity analysis from a randomized controlled trial.Pain medicine (Malden, Mass.) · 2025Trial
- Treatment of Refractory Low Back Pain Using Passive Recharge Burst in Patients Without Options for Corrective Surgery: Findings and Results From the DISTINCT Study, a Prospective Randomized Multicenter Controlled Trial.Neuromodulation : journal of the International Neuromodulation Society · 2023Trial
- The effect of duloxetine on mechanistic pain profiles, cognitive factors and clinical pain in patients with painful knee osteoarthritis-A randomized, double-blind, placebo-controlled, crossover study.European journal of pain (London, England) · 2022Trial
- Sustained effects of auricular point acupressure on chemotherapy-induced neuropathy: a randomized controlled trial follow-up study.Journal of cancer survivorship : research and practice · 2026Article
- FDA-Regulated Clinical Trials vs. Real-World Data: How to Bridge the Gap in Pain Research.Brain sciences · 2025Review
- The Added Value of Digital Body Chart Pain Surface Assessment as an Objective Biomarker: Multicohort Study.Journal of medical Internet research · 2025Observational
- Multidimensional pain assessment and opioid use after total knee arthroplasty: continuous vs single-injection regional vs systemic analgesia.Pain reports · 2025Article
- Chronic postsurgical pain and transitional pain services: a narrative review highlighting European perspectives.Regional anesthesia and pain medicine · 2025Review
- Presurgical anxiety and acute postsurgical pain predict worse chronic pain profiles after total knee/hip arthroplasty.Archives of orthopaedic and trauma surgery · 2025Article
- Validation of a holistic composite outcome measure for the evaluation of chronic pain interventions.Pain reports · 2024Article
- Understanding Kinesiophobia: Predictors and Influence on Early Functional Outcomes in Patients with Total Knee Arthroplasty.Geriatrics (Basel, Switzerland) · 2024Article
- Evaluating the balance of benefits and harms in chronic pain clinical trials: prioritizing individual participants over individual outcomes.Regional anesthesia and pain medicine · 2024Review
- Core patient-reported outcome measures for chronic pain patients treated with spinal cord stimulation or dorsal root ganglia stimulation.Health and quality of life outcomes · 2023Article
- Objective wearable measures and subjective questionnaires for predicting response to neurostimulation in people with chronic pain.Bioelectronic medicine · 2023Article
- Article
- Following Evidence-Based Recommendations for Perioperative Pain Management after Cesarean Section Is Associated with Better Pain-Related Outcomes: Analysis of Registry Data.Journal of clinical medicine · 2023Article
- Cost-effectiveness of the Perioperative Pain Management Bundle a registry-based study.Frontiers in public health · 2023Article
- Combining Awake Anesthesia with Minimal Invasive Surgery Optimizes Intraoperative Surgical Spinal Cord Stimulation Lead Placement.Journal of clinical medicine · 2022Article
- A 6-Month Home-Based Functional Electrical Stimulation Program for Foot Drop in a Post-Stroke Patient: Considerations on a Time Course Analysis of Walking Performance.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.