Evidence map›Paper›PMID 33449510›Full record

Trial reportPain2021

Brief preoperative mind-body therapies for total joint arthroplasty patients: a randomized controlled trial.

Adam W Hanley, Jeremy Gililland, Jill Erickson, Christopher Pelt, Christopher Peters, Jamie Rojas, Eric L Garland

3 registry-linked trialsOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05295004 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of Mindfulness Training Before Primary Total Joint Arthroplasty on Sleep Quality

TypeinterventionalSponsorColorado Joint ReplacementRan2022 to 2024Enrolled282ConditionsSleep Disturbance, ArthropathyArmsMindfulness Meditation Training
NCT06180486 nacompletednot on this mapstarted 2024, after this paper: background citation

Preoperative Mindfulness Meditation for Total Knee Arthroplasty: A Pilot Study

TypeinterventionalSponsorHospital for Special Surgery, New YorkRan2024 to 2025Enrolled30ConditionsTotal Knee Replacement, Mediation, FeasibilityArmsMindfulness Meditation Intervention
NCT06858202 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Structured Post-Operative Pain and Distress Treatment Intervention for Patients Undergoing Surgery for Intra-Abdominal Malignancies

TypeinterventionalSponsorUniversity of UtahRan2025 to 2026Enrolled95ConditionsPsychological Distress, Intra-abdominal CancerArmsMindfulness Intervention, Non-mindfulness Intervention
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

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  15. Commentary onJournal of the Pediatric Orthopaedic Society of North America · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Adam W HanleyCenter on Mindfulness and Integrative Health Intervention Development (C-MIIND), University of Utah College of Social, Salt Lake City, UT, United States.
Jeremy GilillandDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, United States.
Jill EricksonDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, United States.
Christopher PeltDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, United States.
Christopher PetersDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, United States.
Jamie RojasCenter on Mindfulness and Integrative Health Intervention Development (C-MIIND), University of Utah College of Social, Salt Lake City, UT, United States.
Eric L GarlandCenter on Mindfulness and Integrative Health Intervention Development (C-MIIND), University of Utah College of Social, Salt Lake City, UT, United States.
University of Utah · US

Funding

Targeting Hedonic Dysregulation to Address Chronic Pain and Opioid Misuse in Primary Care.R01DA042033 · NIDA · UNIVERSITY OF UTAH · PI GARLAND, ERIC LEE · 2016 to 2020
$2.8M
NIDA NIH HHS R01 DA042033
6 · The paper itself

Abstract

abstractAlthough knee and hip replacements are intended to relieve pain and improve function, up to 44% of knee replacement patients and 27% of hip replacement patients report persistent postoperative joint pain. Improving surgical pain management is essential. We conducted a single-site, 3-arm, parallel-group randomized clinical trial conducted at an orthopedic clinic, among patients undergoing total joint arthroplasty (TJA) of the hip or knee. Mindfulness meditation (MM), hypnotic suggestion (HS), and cognitive-behavioral pain psychoeducation (cognitive-behavioral pain psychoeducation) were each delivered in a single, 15-minute group session as part of a 2-hour, preoperative education program. Preoperative outcomes-pain intensity, pain unpleasantness, pain medication desire, and anxiety-were measured with numeric rating scales. Postoperative physical functioning at 6-week follow-up was assessed with the Patient-Reported Outcomes Measurement Information System Physical Function computer adaptive test. Total joint arthroplasty patients were randomized to preoperative MM, HS, or cognitive-behavioral pain psychoeducation (n = 285). Mindfulness meditation and HS led to significantly less preoperative pain intensity, pain unpleasantness, and anxiety. Mindfulness meditation also decreased preoperative pain medication desire relative to cognitive-behavioral pain psychoeducation and increased postoperative physical functioning at 6-week follow-up relative to HS and cognitive-behavioral pain psychoeducation. Moderation analysis revealed the surgery type did not differentially impact the 3 interventions. Thus, a single session of a simple, scripted MM intervention may be able to immediately decrease TJA patients' preoperative clinical symptomology and improve postoperative physical function. As such, embedding brief MM interventions in surgical care pathways has the potential to improve surgical outcomes for the millions of patients receiving TJA each year.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeHumansKnee JointMind-Body TherapiesPostoperative Pain

Identifiers

PMID33449510
PMCPMC8119303
OpenAlexW3121214190

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.