ArticleHuman brain mapping2021
Development and evaluation of a high performance T1-weighted brain template for use in studies on older adults.
Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- Robustness of NeuroMark-Derived Functional Networks to fMRI Spatial Normalization Across the Human Lifespan.bioRxiv : the preprint server for biology · 2026Article
- Radiomics-based differentiation between glioblastoma and primary central nervous system lymphoma: CT vs MRI.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- Mind the brain age: How segmentation and template selection reshape structural connectomes.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Construction of a Structurally Unbiased Brain Template with High Image Quality from MRI Scans of Saudi Adult Females.Bioengineering (Basel, Switzerland) · 2025Article
- Constructing the KOR152 Korean Young Adult Brain Atlas Utilizing the State-of-the-Art Method for the Age-Specific Population.Psychiatry investigation · 2024Article
- Age-related differences in structural and resting-state functional brain network organization across the adult lifespan: A cross-sectional study.Aging brain · 2024Article
- High resolution 0.5mm isotropic TNeuroImage · 2023Article
- Impaired discourse content in aphasia is associated with frontal white matter damage.Brain communications · 2023Article
- Volumetric brain correlates of gait associated with cognitive decline in community-dwelling older adults.Frontiers in aging neuroscience · 2023Article
- Development of high quality TNeuroImage · 2022Article
- Spatial normalization and quantification approaches of PET imaging for neurological disorders.European journal of nuclear medicine and molecular imaging · 2022Review
- Multi sequence average templates for aging and neurodegenerative disease populations.Scientific data · 2022Article
- Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain.NeuroImage · 2022Article
- Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia.Neurobiology of aging · 2022Article
- Development and evaluation of a high performance T1-weighted brain template for use in studies on older adults.Human brain mapping · 2021Article
- Surface-Guided Image Fusion for Preserving Cortical Details in Human Brain Templates.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted InterventionArticle
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Τhe accuracy of template-based neuroimaging investigations depends on the template's image quality and representativeness of the individuals under study. Yet a thorough, quantitative investigation of how available standardized and study-specific T1-weighted templates perform in studies on older adults has not been conducted. The purpose of this work was to construct a high-quality standardized T1-weighted template specifically designed for the older adult brain, and systematically compare the new template to several other standardized and study-specific templates in terms of image quality, performance in spatial normalization of older adult data and detection of small inter-group morphometric differences, and representativeness of the older adult brain. The new template was constructed with state-of-the-art spatial normalization of high-quality data from 222 older adults. It was shown that the new template (a) exhibited high image sharpness, (b) provided higher inter-subject spatial normalization accuracy and (c) allowed detection of smaller inter-group morphometric differences compared to other standardized templates, (d) had similar performance to that of study-specific templates constructed with the same methodology, and (e) was highly representative of the older adult brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.