Evidence map›Paper›PMID 33449375›Full record

ArticleThe Journal of physiology2021

Location, location, location: the organization and roles of potassium channels in mammalian motoneurons.

Adam S Deardorff, Shannon H Romer, Robert E W Fyffe

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  5. ICA-27243 improves neuromuscular function and preserves motoneurons in the transgenic SOD1Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Article
  6. Persistent NRG1 Type III Overexpression in Spinal Motor Neurons Has No Therapeutic Effect on ALS-Related Pathology in SOD1Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  7. Peptidergic modulation of motor neuron output via CART signaling at C bouton synapses.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Adam S DeardorffDepartment of Neuroscience, Cell Biology and Physiology, Wright State University, Boonshoft School of Medicine, Dayton, OH, 45435, USA.ORCID 0000-0002-0042-0991
Shannon H RomerOdyssey Systems, Environmental Health Effects Laboratory, Navy Medical Research Unit-Dayton, Wright-Patterson Air Force Base, OH, 45433, USA.ORCID 0000-0002-0211-6926
Robert E W FyffeDepartment of Neuroscience, Cell Biology and Physiology, Wright State University, Boonshoft School of Medicine, Dayton, OH, 45435, USA.
Wright State University · USWright-Patterson Air Force Base · US

Funding

Synaptic Function: Effects of the Nerve Injury, Repair, and Altered ActivityP01NS057228 · NINDS · WRIGHT STATE UNIVERSITY · PI COPE, TIMOTHY C · 2007 to 2017
$9.1M
MECHANISMS OF RENSHAW CELL MEDIATED RECURRENT INHIBITIONR01NS025547 · NINDS · WRIGHT STATE UNIVERSITY · PI FYFFE, ROBERT E · 1988 to 2008
$2.3M
NIH HHS NS025547NIH HHS NS057228NINDS NIH HHS P01 NS057228NINDS NIH HHS R01 NS025547
6 · The paper itself

Abstract

The spatial and temporal balance of spinal α-motoneuron (αMN) intrinsic membrane conductances underlies the neural output of the final common pathway for motor commands. Although the complete set and precise localization of αMN K

Indexed as

Motor NeuronsShab Potassium ChannelsAnimalsElectrophysiological PhenomenaMammalsSynapsesShab Potassium Channelsactivity dependentaxon initial segmentC-boutonsHCNKv1Kv2.1Kv7outward currentPICpotassium channelsSKTASKvoltage-gated ion channelsα-motoneuron

Identifiers

PMID33449375
PMCPMC12993820
OpenAlexW3120962138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.