ArticleSpine deformity2021
Sagittal curvature of the spine as a predictor of the pediatric spinal deformity development.
Article in Spine deformity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.
- Current models to understand the onset and progression of scoliotic deformities in adolescent idiopathic scoliosis: a systematic review.Spine deformity · 2023Pooled it
- Kyphosis, lordosis and height velocity. What is the effect of rate of growth on the development of the sagittal parameters of the spine in normal children?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- What can we learn from scoliosis in children with the 22q11.2 deletion syndrome? Prognostic factors at pre-adolescent age for fast progressive, mild and self-resolving forms during adolescence.Spine deformity · 2025Article
- Correlation between coronal wedge deformity and sagittal spinal curvature in adolescent idiopathic scoliosis: a retrospective analysis.Scientific reports · 2024Article
- 22q11.2 Deletion Syndrome as a Human Model for Idiopathic Scoliosis.Journal of clinical medicine · 2021Article
- Quantitative imaging of the spine in adolescent idiopathic scoliosis: shifting the paradigm from diagnostic to comprehensive prognostic evaluation.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021Review
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe sagittal curvature of the spine is hypothesized to play an important role in induction of spinal deformities in adolescent idiopathic scoliosis. We previously showed an S shaped flexible rod, with the same curvature as the pediatric sagittal spinal curve, produces scoliotic-like deformities under physiologic loading. Yet, detailed characteristics of the pediatric sagittal spinal curves associated with higher risk of scoliosis are not well defined.
methodsA total of 32 patients in a population with a high prevalence of idiopathic-like scoliosis, 22q11.2 deletion syndrome (22q), were included and followed up for at least two-years. We developed a reduced order finite element model (FEM) of the sagittal profile of these 32 patients where the spine was modeled as an S shaped elastic rod. We related the geometrical parameters of the sagittal curves and the deformed FEM of the corresponding S shaped rods to the risk of scoliosis development at two-year follow-up in this cohort.
resultsVariations in the sagittal curvature in the cohort of 22q patients resulted in five different deformity patterns shown by finite element analyses. Two sagittal plane deformity pattern groups had high rate of scoliosis development (86% and 100%) whereas the other 3 groups had less than 50% rate of scoliosis development (40%, 33%, and 0%). The pre-scoliotic position of the inflection point (where lordosis turns into kyphosis), the ratio of the spinal curvatures above and below the inflection point, and the length of the spinal curve above and below the inflection point were significantly different between the five deformity patterns groups, p < 0.05.
conclusionCombination of geometrical parameters of the sagittal profile prior to onset of scoliosis can relate to the development of spinal deformity in pediatric population.
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