SynthesisEuropean radiology2021
Efficacy and safety of prostatic artery embolization for benign prostatic hyperplasia: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Effectiveness and Safety of Prostatic Artery Embolization for Patients with Prostate Cancer: A Systematic Review and Meta-Analysis.Cardiovascular and interventional radiology · 2025Pooled it
- Pooled it
- Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a network meta-analysis.The Cochrane database of systematic reviews · 2021Pooled it
- Minimally Invasive Treatment in Benign Prostatic Hyperplasia (BPH).Technology in cancer research & treatmentPooled it
- Digital variance angiography enables up to 80% reduction in stationary acquisition radiation dose during prostatic artery embolization: a prospective randomized trial.European radiology · 2026Trial
- Technical considerations in prostate artery embolization for giant benign prostatic hyperplasia: a case report and literature review.Annals of medicine and surgery (2012) · 2026Article
- Prostatic Artery Embolization: A Contemporary Review of Efficacy, Safety, and Expanding Clinical Indications.Current urology reports · 2026Review
- Article
- Current considerations in prostate artery embolisation.CVIR endovascular · 2026Article
- Review
- Prostatic artery embolization with glue for benign prostatic hyperplasia in elderly patients: three-year results.La Radiologia medica · 2026Article
- One-year outcomes of glue prostate-artery-embolization for symptomatic benign prostatic hyperplasia: a single-center retrospective cohort study.European radiology · 2026Observational
- Comparison of Perioperative Outcomes for Prostate Artery Embolization Versus Transurethral Resection of the Prostate and Laser Enucleation for Benign Prostatic Hyperplasia: Results from the GRAND Study.Journal of clinical medicine · 2025Article
- Comparing embolic particles for prostatic artery embolization to treat lower urinary tract symptoms in patients with benign prostatic hyperplasia.European radiology · 2025Article
- Two-Year Outcomes of Prostatic Artery Embolization for Symptomatic Benign Prostatic Hyperplasia: An International, Multicenter, Prospective Study.Cardiovascular and interventional radiology · 2024Article
- Cost Comparison of Prostatic Artery Embolization Between In-Hospital and Outpatient-Based Lab Settings.Cureus · 2024Article
- Article
- Non-target embolic events during prostatic embolization with ethylene vinyl alcohol copolymer (EVOH).CVIR endovascular · 2023Article
- Influence of benign prostatic hyperplasia patterns detected with MRI on the clinical outcome after prostatic artery embolization.CVIR endovascular · 2023Article
- Nononcologic Embolization.Seminars in interventional radiology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo investigate the efficacy and safety of prostatic artery embolization (PAE) vs. transurethral resection of the prostate (TURP) in patients affected by benign prostatic hyperplasia (BPH). We also reviewed mean changes from baseline in PAE at selected follow-up points.
methodsPubMed, Web of Science, and Embase were searched up to May 1, 2020. Randomized controlled trials on PAE were collected according to specific inclusion and exclusion criteria. Meta-analyses were performed using RevMan 5.3, STATA 14, and GraphPad Prism 8. Pooled patient-reported scores and functional outcomes were calculated by using a fixed or random-effect model.
resultsEleven articles met our selection criteria and ten independent patient series were included in the final analysis. Pooled estimates suggested no significant difference between TURP and PAE for patient-reported outcomes including International Prostate Symptom Score (2.32 (- 0.44 to 5.09)) and quality of life (0.18 (- 0.41 to 0.77)) at 12 months. PAE was less effective regarding improvements in most functional outcomes such as maximum flow rate, prostate volume, and prostate-specific antigen. Moreover, PAE may be associated with relatively fewer complications, lower cost, and shorter hospitalization. After the PAE procedure, the overall weighted mean differences for all outcomes except sexual health scores were significantly improved from baseline during follow-up to 24 months.
conclusionPAE is non-inferior to TURP with regard to improving patient-reported outcomes, though most functional parameters undergo more changes after TURP than after PAE. Moreover, PAE can significantly continue to relieve symptoms for 24 months without causing serious complications. KEY POINTS: • PAE is as effective as TURP in improving subjective symptom scores, with fewer complications and shorter hospitalization times. • PAE is inferior to TURP in the improvement of most functional outcomes. • Improvements due to PAE are durable during follow-up to 24 months.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.