ReviewCellular and molecular life sciences : CMLS2021
Cell signaling regulation in salivary gland development.
Review in Cellular and molecular life sciences : CMLS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 39 citations in OpenAlex.
- Effect of high-sucrose intake on the salivary glands of growing rats: histological analysis and assessment of gene and protein expression.Odontology · 2026Article
- Developmental Differences in Circular RNA Expression Between Adult and Fetal Human Salivary Glands Based on Public Total RNA-Sequencing Data.International journal of molecular sciences · 2026Article
- Role of Ki-67 and Annexin V in the Biological Behavior of Salivary Gland Tumors: Insights into Proliferation and Apoptosis.Current issues in molecular biology · 2026Article
- Unveiling critical signaling pathways in the murine salivary gland and the role of midkine.iScience · 2026Article
- Salivary gland cell senescence in Sjögren's syndrome: current research and novel therapeutic directions.Immunity & ageing : I & A · 2025Review
- Saliva as a Diagnostic Tool for Systemic Diseases-A Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Salivary gland stem/progenitor cells: advancing from basic science to clinical applications.Cell regeneration (London, England) · 2025Review
- Biomimetic Catechol-Incorporated Polyacrylonitrile Nanofiber Scaffolds for Tissue Engineering of Functional Salivary Glands.Biomaterials research · 2025Article
- Developing and regenerating a sense of taste.Current topics in developmental biology · 2025Review
- Neuropeptides regulate embryonic salivary gland branching through the FGF/FGFR pathway in aging klotho-deficient mice.Aging cell · 2024Article
- TGF-β1 maintains the developmental potential of embryonic submandibular gland epithelia separated with mesenchyme.Heliyon · 2024Article
- Transcription factor FoxO1 regulates myoepithelial cell diversity and growth.Scientific reports · 2024Article
- Maintenance of adult stem cells from human minor salivary glands via the Wnt signaling pathway.Stem cell research & therapy · 2023Article
- Inflationary theory of branching morphogenesis in the mouse salivary gland.Nature communications · 2023Article
- Developmental function of Piezo1 in mouse submandibular gland morphogenesis.Histochemistry and cell biology · 2023Article
- Autologous mesenchymal stem cells offer a new paradigm for salivary gland regeneration.International journal of oral science · 2023Review
- A cellular hierarchy of Notch and Kras signaling controls cell fate specification in the developing mouse salivary gland.Developmental cell · 2023Article
- Bulk RNA-seq and scRNA-seq analysis reveal an activation of immune response and compromise of secretory function in major salivary glands of obese mice.Computational and structural biotechnology journal · 2023Article
- Identification of a novel mutation in theInternational journal of ophthalmology · 2023Article
- Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states.International journal of molecular medicine · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
The mammalian salivary gland develops as a highly branched structure designed to produce and secrete saliva. This review focuses on research conducted on mammalian salivary gland development, particularly on the differentiation of acinar, ductal, and myoepithelial cells. We discuss recent studies that provide conceptual advances in the understanding of the molecular mechanisms of salivary gland development. In addition, we describe the organogenesis of submandibular glands (SMGs), model systems used for the study of SMG development, and the key signaling pathways as well as cellular processes involved in salivary gland development. The findings from the recent studies elucidating the identity of stem/progenitor cells in the SMGs, and the process by which they are directed along a series of cell fate decisions to form functional glands, are also discussed. Advances in genetic tools and tissue engineering strategies will significantly increase our knowledge about the mechanisms by which signaling pathways and cells establish tissue architecture and function during salivary gland development, which may also be conserved in the growth and development of other organ systems. An increased knowledge of organ development mechanisms will have profound implications in the design of therapies for the regrowth or repair of injured tissues. In addition, understanding how the processes of cell survival, expansion, specification, movement, and communication with neighboring cells are regulated under physiological and pathological conditions is critical to the development of future treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.