Evidence map›Paper›PMID 33449098›Full record

ArticleJAMA network open2021

Facility-Level Variation in Dialysis Use and Mortality Among Older Veterans With Incident Kidney Failure.

Christina Bradshaw, I-Chun Thomas, Maria E Montez-Rath, Karl A Lorenz, Steven M Asch, John T Leppert, Virginia Wang, Ann M O'Hare, Manjula Kurella Tamura

Open access · goldAbstract read
In one paragraph

Article in JAMA network open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Christina BradshawDivision of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California.
I-Chun ThomasGeriatric Research and Education Clinical Center, Veterans Affairs (VA) Palo Alto Health Care System, Palo Alto, California.
Maria E Montez-RathDivision of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California.
Karl A LorenzCenter for Innovation to Implementation, VA Palo Alto Health Care System, Palo Alto, California.
Steven M AschCenter for Innovation to Implementation, VA Palo Alto Health Care System, Palo Alto, California.
John T LeppertDivision of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California.
Virginia WangCenter of Innovation for Health Services Research, Durham VA Health Care System, Durham, North Carolina.
Ann M O'HareHospital and Specialty Medicine Service, VA Puget Sound Health Care System, Seattle, Washington.
Manjula Kurella TamuraDivision of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California.
Stanford University · USVA Palo Alto Health Care System · USCenter for Innovation · USDurham VA Health Care System · USVA Puget Sound Health Care System · US

Funding

Ethical provision of hemodialysis: Patients' perspectives on financial hardship and physician counseling in IndiaF32DK118795 · NIDDK · STANFORD UNIVERSITY · PI BRADSHAW, CHRISTINA LEIGH · 2018 to 2018
$82k
NIDDK NIH HHS F32 DK118795
6 · The paper itself

Abstract

Importance: Current guidelines lack consensus regarding the treatment of patients who may not benefit from dialysis; this lack of consensus may be associated with the substantial variation in dialysis use and outcomes across health care facilities. Objective: To assess the degree to which variation in dialysis use and mortality was associated with patient rather than facility characteristics and to distinguish which features identified the US Department of Veterans Affairs (VA) facilities with high rates of dialysis use. Design, Setting, and Participants: This cohort study analyzed data of veterans with stage 3 or 4 chronic kidney disease that progressed to kidney failure between January 1, 2011, and December 31, 2014. These patients received care from VA facilities across the US. Data sources included laboratory and administrative records from the VA, Medicare, and United States Renal Data System. Data analysis was conducted from August 1, 2019, to September 1, 2020. Exposures: The primary exposure was the VA facility in which patients received most of their care before the onset of incident kidney failure defined as the first occurrence of either a sustained estimated glomerular filtration rate of less than 15 mL/min/1.73 m2 or the initiation of maintenance dialysis. Main Outcomes and Measures: The primary outcomes were dialysis use and mortality within 2 years of incident kidney failure. Median rate ratio was used to quantify facility-level variation, and variance partition coefficient was used to quantify the sources of unexplained variation. Results: The cohort included 8695 older veterans with a mean (SD) age of 78.8 (7.5) years who were predominantly male (8573 [99%]) and White (6102 [70%]) individuals treated at 108 VA facilities. The observed frequency of dialysis use across facilities ranged from 25.0% to 81.4%, with a median (interquartile range [IQR]) rate of 51.7% (48.4%-60.0%). The observed frequency of mortality across facilities ranged from 27.2% to 60.0%, with a median (IQR) rate of 45.2% (41.2%-48.6%). The median rate ratio (adjusted for multiple patient and facility characteristics) was 1.40 for dialysis use and 1.08 for mortality. The unexplained variation in both outcomes mainly derived from patient characteristics rather than facility characteristics. No correlation was found between dialysis use and mortality at the facility level (correlation coefficient = 0.03). Conclusions and Relevance: This study found sizable variation in dialysis use for older adults that was poorly correlated with facility-level mortality rates and was not accounted for by differences in measured patient and facility characteristics. These findings suggest opportunities to improve the degree to which dialysis use practices align with the values, goals, and preferences of older adults with kidney failure.

Indexed as

VeteransAgedFemaleHumansMalePractice Patterns, Physicians'Renal DialysisRenal InsufficiencyUnited StatesUnited States Department of Veterans Affairs

Identifiers

PMID33449098
PMCPMC7811178
OpenAlexW3119776325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.