ArticleeLife2021
Female-biased upregulation of insulin pathway activity mediates the sex difference in
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 62 citations in OpenAlex.
- Insulin receptor signaling in gustatory cells suppresses sugar taste sensitivity and feeding iniScience · 2026Article
- Sex of central neurons controls intestinal niche signalling to drive sex differences in stem cell activity and cancer susceptibility.Nature communications · 2026Article
- Gut-derived Unpaired-3 cytokine signaling promotes systemic hypoxia tolerance in Drosophila.Disease models & mechanisms · 2026Article
- Sex differences in the regulation and function of cellular immunity in Drosophila.PLoS genetics · 2026Article
- Article
- Private QTLs and the genetic architecture of hierarchical size traits: from body size to sex-specific plasticity.G3 (Bethesda, Md.) · 2026Article
- Host insulin hijacking by a nematode receptor mediates developmental plasticity and sex ratio shifts.Nature communications · 2026Article
- Response of Protein Coding Genes and microRNAs to Temperature Changes in Four Species of Drosophilids.Genome biology and evolution · 2026Article
- Gut hormone signaling drives sex differences in metabolism and behavior.Molecular metabolism · 2026Article
- Insulin and epidermal signals independently shape sexually dimorphic neurite branching in C. elegans.EMBO reports · 2025Article
- The insulin-like peptides Dilp2 and Dilp6 exhibit divergent responses to dietary sugar and protein inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Sex-converted testis somatic cells acquire female-specific behaviors and alter XY germline identity.Development (Cambridge, England) · 2025Article
- Tissue-specific metabolomic signatures for aRoyal Society open science · 2025Article
- Gut microbe-derived lactic acid optimizes host energy metabolism during starvation.bioRxiv : the preprint server for biology · 2025Article
- Elevated ambient temperature reduces fat storage through the FoxO-mediated insulin signaling pathway.PloS one · 2025Article
- Sex-dimorphic tumor growth is regulated by tumor microenvironmental and systemic signals.Science advances · 2024Article
- Improvement of starvation resistance via periodic fasting is genetically variable inPhysiological entomology · 2024Article
- Cellular sex throughout the organism underlies somatic sexual differentiation.Nature communications · 2024Article
- Soma-germline communication drives sex maintenance in theNational science review · 2024Article
- Consideration of sex as a biological variable in diabetes research across twenty years.Biology of sex differences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Nutrient-dependent body size plasticity differs between the sexes in most species, including mammals. Previous work in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.