Evidence map›Paper›PMID 33448177›Full record

ArticleZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2020

[Differentially expressed inflammatory proteins in acute gouty arthritis based on protein chip].

Guanghan Sun, Jian Liu, Lei Wan, Wei Liu, Yan Long, Bingxi Bao, Ying Zhang

Open access · greenAbstract read
In one paragraph

Article in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. [Association of metabolic syndrome and its components with gout: an analysis based on a large-scale health survey database].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Guanghan SunDepartment of Rheumatology and Immunology, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230031, China.
Jian LiuDepartment of Rheumatology and Immunology, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230031, China.
Lei WanDepartment of Rheumatology and Immunology, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230031, China.
Wei LiuDepartment of Rheumatology and Immunology, the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China.
Yan LongDepartment of Rheumatology and Immunology, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230031, China.
Bingxi BaoDepartment of Rheumatology and Immunology, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230031, China.
Ying ZhangDepartment of Rheumatology and Immunology, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230031, China.
Anhui University of Traditional Chinese Medicine · CNTianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo detect the differentially expressed inflammatory proteins in acute gouty arthritis (AGA) with protein chip.

methodsThe Raybiotech cytokine antibody chip was used to screen the proteomic expression in serum samples of 10 AGA patients and 10 healthy individuals. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis were applied to determine the biological function annotation of differentially expressed proteins and the enrichment of signal pathways. ELISA method was used to verify the differential protein expression in 60 AGA patients and 60 healthy subjects. The ROC curve was employed to evaluate the diagnostic value of differential proteins in AGA patients.

resultsAccording to|log

conclusionsProteomics can be applied to identify the biomarkers of AGA, which may be used for risk prediction and diagnosis of AGA patients.

Indexed as

Arthritis, GoutyGene Expression RegulationProtein Array AnalysisCytokinesGene Expression ProfilingHumansInflammationProteomicsCytokinesAcute gouty arthritisBiomarkersInflammatory functionProteomics

Identifiers

PMID33448177
PMCPMC10412413
OpenAlexW3119736841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.