ArticleInternational orthopaedics2021
Total knee arthroplasty improves the quality-adjusted life years in patients who exceeded their estimated life expectancy.
Article in International orthopaedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Clinical prediction models for postoperative blood transfusion after total knee arthroplasty: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Enhanced recovery after surgery protocols in total knee arthroplasty via midvastus approach: a randomized controlled trial.BMC musculoskeletal disorders · 2021Trial
- Comparison of Routine Posterior Cruciate Ligament Resection vs Selective PCL Balancing Using a Medial Congruent Polyethylene in Total Knee Arthroplasty: A Matched-Cohort Analysis.Arthroplasty today · 2026Article
- Evaluating Patient Satisfaction Outcome After Total Knee Arthroplasty Done at Our Hospital's Joint Replacement Registry, Egypt.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Observational
- Association of Sugammadex Exposure with Venous Thrombosis Risk Following Primary Total Knee Arthroplasty: A Multi-Institutional Retrospective Analysis.Drug design, development and therapy · 2026Article
- Risk Factors for Physiologic Radiolucent Lines Under the Tibial Base Plate After Osteoarthritis With Primary Computer-Assisted Navigation TKA-A Nested Case-Control Study.Orthopaedic surgery · 2025Article
- Article
- Does the Type of Knee Arthroplasty Affect the Patient's Postural Stability?Medicina (Kaunas, Lithuania) · 2024Article
- Severe genu varus deformity does not affect enhanced recovery after surgery total knee arthroplasty outcomes.Archives of orthopaedic and trauma surgery · 2024Article
- Multidisciplinary approach toward enhanced recovery after surgery for total knee arthroplasty improves outcomes.World journal of clinical cases · 2024Article
- Cemented vs. Cementless Fixation in Primary Knee Replacement: A Narrative Review.Materials (Basel, Switzerland) · 2024Review
- Global mapping of institutional and hospital-based (Level II-IV) arthroplasty registries: a scoping review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- RETRACTED: Enhanced wound recovery after surgery care in patients with total knee arthroplasty: A meta-analysis.International wound journal · 2024Review
- Implant Preference and Clinical Outcomes of Patients with Staged Bilateral Total Knee Arthroplasty: All-Polyethylene and Contralateral Metal-Backed Tibial Components.Journal of clinical medicine · 2023Article
- The dynamic impact of Joint Awareness on Quality of Life after Total Knee Arthroplasty: a longitudinal study.Journal of orthopaedic surgery and research · 2022Article
- Article
- CoenzymeQ10 and Ischemic Preconditioning Potentially Prevent Tourniquet-Induced Ischemia/Reperfusion in Knee Arthroplasty, but Combined Pretreatment Possibly Neutralizes Their Beneficial Effects.Antioxidants (Basel, Switzerland) · 2022Article
- Comment on article by Palazzuolo et al.: Total knee arthroplasty improves the quality-adjusted life years in patients who exceeded their estimated life expectancy.International orthopaedics · 2021Article
- Cementless, Cruciate-Retaining Primary Total Knee Arthroplasty Using Conventional Instrumentation: Technical Pearls and Intraoperative Considerations.JBJS essential surgical techniquesArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTotal knee arthroplasty (TKA) is the treatment of choice for end-stage osteoarthritis though its risk-benefit ratio in elderly patients remains debated. This study aimed to evaluate the functional outcome, rates of complication and mortality, and quality-adjusted life years (QALY) in patients who exceeded their estimated life expectancy.
methodsNinety-seven TKA implanted in 86 patients who exceeded their estimated life expectancy at the time of TKA were prospectively included in our institutional joint registry and retrospectively analyzed. At latest follow-up, the functional outcome with the Knee Society Score (KSS), rates of complication and mortality, and QALY with utility value of EuroQol-5D score were evaluated.
resultsAt a mean follow-up of three ± one years, the pre- to post-operative KSS improved significantly (p < 0.01). The rates of surgical and major medical complications related to TKA were 3% and 10%, respectively. The re-operation rate with readmission was 3% while no TKA was revised. The 30-day and one year mortality was 1% and 3%, respectively. The pre- to one year post-operative QALY improved significantly (p < 0.01). The cumulative QALY five years after TKA was four years. Assuming that these patients did not undergo TKA, their cumulative QALY at five years would have been only two years.
conclusionTKA is an effective procedure for the treatment of end-stage osteoarthritis in patients who exceeded their estimated life expectancy. TKA provided significant improvement in function and quality of life without adversely affecting overall morbidity and mortality. Therefore, TKA should not be contra-indicated in elderly patients based on their advanced age alone.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.