Evidence map›Paper›PMID 33447768›Full record

ArticleInternational Journal of Cardiology. Hypertension2020

The effect of feedback on cardiovascular risk factors on optimization of primary prevention: The PharmLines initiative.

M Yldau van der Ende, Ingmar E Waardenburg, E Lipsic, Jens H J Bos, Eelko Hak, H Snieder, Pim van der Harst

Open access · goldAbstract read
In one paragraph

Article in International Journal of Cardiology. Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

M Yldau van der EndeUniversity of Groningen, University Medical Center Groningen, The Department of Cardiology, Groningen, the Netherlands.
Ingmar E WaardenburgUniversity of Groningen, University Medical Center Groningen, The Department of Cardiology, Groningen, the Netherlands.
E LipsicUniversity of Groningen, University Medical Center Groningen, The Department of Cardiology, Groningen, the Netherlands.
Jens H J BosPharmacoTherapy, Epidemiology & Economics, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, the Netherlands.
Eelko HakPharmacoTherapy, Epidemiology & Economics, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, the Netherlands.
H SniederUniversity of Groningen, University Medical Center Groningen, The Department of Epidemiology, Groningen, the Netherlands.
Pim van der HarstUniversity of Groningen, University Medical Center Groningen, The Department of Cardiology, Groningen, the Netherlands.
University of Groningen · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is unknown whether population based single assessment of cardiovascular disease (CVD) risk and feedback to individuals and general practitioners results in initiation of preventive cardiovascular pharmacotherapy in those at risk.

methodsThe population based cohort study Lifelines was linked to the IADB.nl pharmacy database to assess information on the initiation of preventive medication (

resultsBefore the Lifelines baseline visit, 34% (out of 1,527, 95% Confidence interval (CI) 32%-36%) and 30% (out of 1,991, 95%CI 28%-32%) of the individuals at risk had a blood pressure or lipid lowering drug prescription, respectively. In those at risk, the use of blood pressure lowering medication, increased substantially during the year of the baseline visit. Treating individuals at increased risk (≥5% 10-year risk) with lipid or blood pressure lowering medication (

conclusionPrimary prevention of CVD in the general population appears suboptimal. Feedback of cardiovascular risk factors resulted in a substantial increase of blood pressure lowering medication and extrapolated health benefits.

Indexed as

Cardiovascular diseaseLifelinesPrimary preventionRisk assessmentRisk factors

Identifiers

PMID33447768
PMCPMC7803074
OpenAlexW3045718473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.