Evidence map›Paper›PMID 33447738›Full record

ArticleInternational Journal of Cardiology. Hypertension2019

Electrocardiography for diagnosis of left ventricular hypertrophy in hypertensive patients with atrial fibrillation.

Fabio Angeli, Paolo Verdecchia, Claudio Cavallini, Adolfo Aita, Dario Turturiello, Giovanni Mazzotta, Monica Trapasso, Michelantonio De Fano, Gianpaolo Reboldi, Umbria-Atrial Fibrillation Study Group

Abstract read
In one paragraph

Article in International Journal of Cardiology. Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fabio AngeliDivision of Cardiology and Cardiovascular Pathophysiology, Hospital S. Maria Della Misericordia, Perugia, Italy.
Paolo VerdecchiaFondazione Umbra Cuore e Ipertensione-ONLUS, Division of Cardiology, Hospital S. Maria Della Misericordia, Perugia, Italy.
Claudio CavalliniFondazione Umbra Cuore e Ipertensione-ONLUS, Division of Cardiology, Hospital S. Maria Della Misericordia, Perugia, Italy.
Adolfo AitaFondazione Umbra Cuore e Ipertensione-ONLUS, Division of Cardiology, Hospital S. Maria Della Misericordia, Perugia, Italy.
Dario TurturielloDivision of Cardiology and Cardiovascular Pathophysiology, Hospital S. Maria Della Misericordia, Perugia, Italy.
Giovanni MazzottaFondazione Umbra Cuore e Ipertensione-ONLUS, Division of Cardiology, Hospital S. Maria Della Misericordia, Perugia, Italy.
Monica TrapassoDepartment of Medicine, University of Perugia, Perugia, Italy.
Michelantonio De FanoDepartment of Medicine, University of Perugia, Perugia, Italy.
Gianpaolo ReboldiDepartment of Medicine, University of Perugia, Perugia, Italy.
Umbria-Atrial Fibrillation Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular (LV) hypertrophy at electrocardiography (ECG) predicts incident atrial fibrillation (AF). However, the diagnostic performance of ECG for diagnosis of LV hypertrophy in patients with AF is still not well characterized. We analyzed 563 hypertensive patients enrolled in the Umbria-Atrial Fibrillation (Umbria-FA) registry, an ongoing prospective observational registry in patients with AF. All patients underwent ECG and standard echocardiography at their entry in the Register. Mean age was 74 years and 43% of patients were women. Prevalence of ECG-LV hypertrophy, defined by Perugia criterion corrected for body mass index, was 23%. Echocardiographic LV mass was the reference standard. Sensitivity, specificity and diagnostic accuracy of ECG-LV hypertrophy were 37.4% (95% confidence interval [CI]: 31.6-43.4), 90.0% (95% CI: 86.0-93.2) and 64.5% (95% CI: 60.4-68.3), respectively. Performance was comparable in patients with AF or sinus rhythm at ECG recording. The area under the receiver-operating characteristic (ROC) curve was 0.622 (95% CI: 0.580-0.664) in the group with AF and 0.662 (95% CI: 0.605-0.720) in that with sinus rhythm (p ​= ​0.266 for comparison). These data suggest that standard ECG is reliable for diagnosis of LV hypertrophy in patients with a history of AF, regardless of the presence of AF or sinus rhythm at the time of ECG recording.

Indexed as

Atrial fibrillationDiagnosisElectrocardiographyHypertensionLeft ventricular hypertrophy

Identifiers

PMID33447738
PMCPMC7803070

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.