Evidence map›Paper›PMID 33447724›Full record

ArticleEuropean heart journal. Case reports2020

Acute heart and brain failure: a case report.

Magdalena Stuetz, Christian Templin, Jelena-Rima Templin-Ghadri, Frank Ruschitzka, Heiko Pohl, Daniel Hofer

Abstract read
In one paragraph

Article in European heart journal. Case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Magdalena StuetzDepartment of Cardiology, University Heart Center Zurich, University Hospital Zurich, Raemistrasse 100, 8006 Zurich, Switzerland.ORCID 0000-0002-3091-5178
Christian TemplinDepartment of Cardiology, University Heart Center Zurich, University Hospital Zurich, Raemistrasse 100, 8006 Zurich, Switzerland.ORCID 0000-0003-0287-4193
Jelena-Rima Templin-GhadriDepartment of Cardiology, University Heart Center Zurich, University Hospital Zurich, Raemistrasse 100, 8006 Zurich, Switzerland.
Frank RuschitzkaDepartment of Cardiology, University Heart Center Zurich, University Hospital Zurich, Raemistrasse 100, 8006 Zurich, Switzerland.ORCID 0000-0001-5972-0596
Heiko PohlDepartment of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland.ORCID 0000-0002-2778-6790
Daniel HoferDepartment of Cardiology, University Heart Center Zurich, University Hospital Zurich, Raemistrasse 100, 8006 Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTakotsubo syndrome (TTS) is characterized by often reversible but acute heart failure occurring after an emotional or physical trigger event. The 'brain failure' counterpart is posterior reversible encephalopathy syndrome (PRES) characterized by often reversible but acute neurological symptoms. This case report elaborates on a complex clinical scenario with co-existence of coronary artery disease, TTS and PRES and discusses the pathophysiology, differential diagnosis, and management. CASE SUMMARY: An 82-year-old woman presented with acute heart failure and generalized tonic-clonic seizures following an acute exacerbation of her chronic back pain. Brain magnetic resonance imaging demonstrated vasogenic oedema consistent with the diagnosis of PRES. Focal wall motion abnormalities on echocardiography without causal coronary stenoses on angiography were consistent with the diagnosis of TTS. After an interdisciplinary approach to differential diagnosis and treatment, the patient was discharged to geriatric rehabilitation without heart failure or neurological defects 4 weeks later. DISCUSSION: TTS and PRES share significant similarities in proposed pathogenesis, epidemiology, management, and clinical outcome. This case report highlights the need for early recognition of this rare association and multidisciplinary approach to diagnosis and treatment as both heart and brain disease may require early intervention up to rapid intensive care support.

Indexed as

Apical ballooningBrain heart interactionBroken heart syndromeCase reportPosterior reversible encephalopathy syndromeTakotsubo syndrome

Identifiers

PMID33447724
PMCPMC7793236

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.