Evidence map›Paper›PMID 33447584›Full record

ReviewGland surgery2020

Pitfalls and differential diagnosis on adrenal lesions: current concepts in CT/MR imaging: a narrative review.

Alfonso Reginelli, Giovanna Vacca, Mariapaola Belfiore, Angelo Sangiovanni, Valerio Nardone, Angelo Vanzulli, Roberto Grassi, Salvatore Cappabianca

Abstract readReview
In one paragraph

Review in Gland surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Molecular imaging and radionuclide therapy · 2026
    Article
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  6. Review
  7. Review
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  15. Adrenal Lesions: A Review of Imaging.Diagnostics (Basel, Switzerland) · 2022
    Review
  16. Article
  17. Review
  18. Article
  19. Adrenal myelolipomas.The lancet. Diabetes & endocrinology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alfonso ReginelliDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Giovanna VaccaDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Mariapaola BelfioreDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Angelo SangiovanniDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Valerio NardoneUnit of Radiation Oncology, Ospedale del Mare, Naples, Italy.
Angelo VanzulliDepartment of Radiology, University "La Statale" of Milan, Milan, Italy.
Roberto GrassiDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Salvatore CappabiancaDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this pictorial essay is to review the imaging findings of adrenal lesions. Adrenal lesions could be divided into functioning or non-functioning masses, primary or metastatic, and benign or malignant. Imaging techniques have undergone significant advances in recent years. The most significant objective of adrenal imaging is represented by the detection and, when possible, characterization of adrenal lesions in order to direct patient management correctly. The detection and management of adrenal lesions is based on cross-sectional imaging obtained with non-contrast CT (tumour density), contrast-enhanced CT including delayed washout (either absolute percentage washout or relative percentage one) and finally with MR chemical shift analysis (loss of signal intensity between in-phase and out-of-phase images including both qualitative and quantitative estimates of signal loss). The small incidental adrenal nodules are benign, in most of cases; some tumors such as lipid-rich adenoma and myelolipoma have characteristic features that can be diagnosed accurately in CT. On contrary, if the presenting contrast-enhanced CT shows an adrenal mass with uncertain or malignant morphologic features, particularly in patients with a known history of malignancy, further evaluations should be considered. The most significative implications for radiologists are represented by how to assess risk of malignancy on imaging and what follow-up to indicate if an adrenal incidentaloma is not surgically removed.

Indexed as

Adrenal glandadrenal masses diagnosiscomputed tomographymagnetic resonance imaging

Identifiers

PMID33447584
PMCPMC7804564

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.