Evidence map›Paper›PMID 33447349›Full record

ArticleOncotarget2020

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution's experience.

Alexandros Diamantis, Athina A Samara, Dimitrios Symeonidis, Ioannis Baloyiannis, Dionysia Vasdeki, Maria Tolia, Georgios Volakakis, Georgios Mavrovounis, Konstantinos Tepetes

Abstract read
In one paragraph

Article in Oncotarget, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Wandering small intestinal stromal tumor: A case report.World journal of clinical cases · 2022
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandros DiamantisDepartment of General Surgery, University Hospital of Larisa, Mezourlo, Larisa, Thessaly, Greece.
Athina A SamaraDepartment of General Surgery, University Hospital of Larisa, Mezourlo, Larisa, Thessaly, Greece.
Dimitrios SymeonidisDepartment of General Surgery, University Hospital of Larisa, Mezourlo, Larisa, Thessaly, Greece.
Ioannis BaloyiannisDepartment of General Surgery, University Hospital of Larisa, Mezourlo, Larisa, Thessaly, Greece.
Dionysia VasdekiDepartment of General Surgery, University Hospital of Larisa, Mezourlo, Larisa, Thessaly, Greece.
Maria ToliaDepartment of Radiotherapy/Radiation Oncology, Faculty of Medicine, School of Health Sciences, University of Crete, University Hospital of Heraklion, Crete, Greece.
Georgios VolakakisDepartment of General Surgery, University Hospital of Larisa, Mezourlo, Larisa, Thessaly, Greece.
Georgios MavrovounisDepartment of General Surgery, University Hospital of Larisa, Mezourlo, Larisa, Thessaly, Greece.
Konstantinos TepetesDepartment of General Surgery, University Hospital of Larisa, Mezourlo, Larisa, Thessaly, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal stromal tumors (GISTs) quite often co-exist with other primary tumors, as seen in up to 33% of cases. In the literature such occurrences have primarily been described through case reports and rarely through case series, which is not sufficient to prove if there is an association between these two entities. MATERIALS AND

methodsWe conducted a retrospective study using medical and pathological records from sixty-nine patients who underwent surgical treatment for GIST in a single university surgical department between 2011 and 2019. Seven cases of GIST accompanying a synchronous primary tumor were identified and included in the study.

resultsSurvival analysis comparing the overall survival of patients with single GIST versus patients with concurrent GIST and another primary tumor, has shown no statistically significant difference between these two groups (

conclusionsThe synchronous occurrence of GISTs and other intra-abdominal tumors is more common than previously considered, though it is not yet clear if there is a causal association for the concomitant occurrence. Further studies are required to elucidate the genetic and molecular mechanisms of carcinogenesis and progression associating GIST and synchronous tumors.

Indexed as

gastrointestinal stromal tumormesenchymal tumorssynchronous malignancies

Identifiers

PMID33447349
PMCPMC7779251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.