Evidence map›Paper›PMID 33447317›Full record

ArticleJournal of clinical medicine research2020

Severe Non-Islet Cell Hypoglycemia From Ileum-Origin Gastrointestinal Stromal Tumor Producing Insulin-Like Growth Factor-2 in a Patient With Liver Cirrhosis Due to Chronic Hepatitis B.

Kohzo Takebayashi, Sho Furukawa, Takenori Okumura, Mio Kubo, Atsushi Ujiie, Mototaka Yamauchi, Hiroyuki Shinozaki, Kenji Hara, Takafumi Tsuchiya, Yuko Ono and 2 more

Abstract readCase Reports
In one paragraph

Article in Journal of clinical medicine research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kohzo TakebayashiDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Sho FurukawaDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Takenori OkumuraDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Mio KuboDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Atsushi UjiieDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Mototaka YamauchiDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Hiroyuki ShinozakiDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Kenji HaraDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Takafumi TsuchiyaDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Yuko OnoDepartment of Pathology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.
Toshihiko InukaiDepartment of Internal Medicine, Seibu General Hospital, Omiya, Saitama, Japan.
Koshi HashimotoDepartment of Diabetes, Endocrinology and Hematology, Dokkyo Saitama Medical Center, Koshigaya, Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome, and NICTH associated with gastrointestinal stromal tumor (GIST) is even more rare. Herein, we describe a patient with severe NICTH due to GIST who had developed liver cirrhosis as a consequence of chronic hepatitis B. Although circulating insulin, C-peptide, and insulin-like growth factor-1 (IGF-1) levels were significantly decreased, in contrast to our expectations, the growth hormone (GH) level was slightly elevated. Steroid therapy with prednisolone appeared to be effective for the prevention of severe and continuous hypoglycemia.

Indexed as

GISTLiver cirrhosisNICTHSteroid therapy

Identifiers

PMID33447317
PMCPMC7781283

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.