Evidence map›Paper›PMID 33447235›Full record

ReviewBreast care (Basel, Switzerland)2020

Therapy Algorithms for the Diagnosis and Treatment of Patients with Early and Advanced Breast Cancer.

Andreas Schneeweiss, Ingo Bauerfeind, Tanja Fehm, Wolfgang Janni, Christoph Thomssen, Isabell Witzel, Achim Wöckel, Volkmar Müller

Open access · hybridAbstract readReview
In one paragraph

Review in Breast care (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Andreas SchneeweissNational Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany.
Ingo BauerfeindClinic for Gynecology and Obstetrics, Landshut, Germany.
Tanja FehmDepartment of Gynecology and Obstetrics, University Hospital, Düsseldorf, Germany.
Wolfgang JanniDepartment of Gynecology and Obstetrics, University Hospital, Ulm, Germany.
Christoph ThomssenDepartment of Gynecology and Obstetrics, University Hospital, Halle, Germany.
Isabell WitzelDepartment of Gynecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Achim WöckelDepartment of Gynecology and Obstetrics, University Hospital, Würzburg, Germany.
Volkmar MüllerDepartment of Gynecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Universität Hamburg · DEDüsseldorf University Hospital · DEGerman Cancer Research Center · DEUniversitätsklinikum Würzburg · DEUniversity Hospital in Halle · DEUniversity Hospital Ulm · DEUniversity of Applied Sciences Landshut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn order to offer optimal treatment approaches based on available evidence, the Commission Breast of the Working Group Gynecologic Oncology (AGO) of the German Cancer Society developed therapy algorithms for eight complex treatment situations in primary and advanced breast cancer. SUMMARY: Therapy algorithms for the following complex treatment situations are outlined in this paper: (neo)adjuvant therapy of human epidermal growth factor receptor 2 (HER2)-positive breast cancer; axillary surgery and neoadjuvant chemotherapy; adjuvant endocrine therapy in premenopausal patients; adjuvant endocrine therapy in postmenopausal patients; hormone receptor (HR)-positive/HER2-negative metastatic breast cancer: strategies; HR-positive/HER2-negative metastatic breast cancer: endocrine-based first-line treatment; HER2-positive metastatic breast cancer: first to third-line; metastatic triple-negative breast cancer. KEY MESSAGES: The therapy options shown in these algorithms are based on the current AGO recommendations updated in January 2020 but cannot represent all evidence-based treatment options. Prior therapies, performance status, comorbidities, patient preference, etc. must be taken into account for the actual treatment choice. Therefore, in individual cases, other evidence-based treatment options not listed here may also be appropriate and justified.

Indexed as

Breast cancer guidelinesEvidence-based treatmentTherapy algorithms

Identifiers

PMID33447235
PMCPMC7768141
OpenAlexW3095067634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.