Evidence map›Paper›PMID 33447039›Full record

ArticleVascular health and risk management2020

Clinical Characteristics, Treatment Outcomes, and its Predictors Among Hospitalized Stroke Patients in Ambo University Referral Hospital, West Ethiopia: A Retrospective Hospital-Based Study.

Diriba Alemayehu Gadisa, Guye Betero Busawa, Esayas Tadesse Gebremariam, Gosaye Mekonen Tefera, Kefyalew Taye Belete, Getu Melesie Taye, Lemma Bose Meskele, Biruk Mosisa Gudeta, Belayneh Kefale Gelaw

Open access · goldAbstract read
In one paragraph

Article in Vascular health and risk management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Diriba Alemayehu GadisaDepartment of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.ORCID 0000-0002-3972-4175
Guye Betero BusawaDepartment of Pharmacy, College of Medicine and Health Sciences, Bule Hora University, Bule Hora, Ethiopia.ORCID 0000-0001-6289-6461
Esayas Tadesse GebremariamDepartment of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.ORCID 0000-0002-9090-3590
Gosaye Mekonen TeferaDepartment of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.ORCID 0000-0002-7534-2828
Kefyalew Taye BeleteDepartment of Public Health, College of Medicine and Health Science, Ambo University, Ambo, Ethiopia.ORCID 0000-0002-2544-8763
Getu Melesie TayeDepartment of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.
Lemma Bose MeskeleDepartment of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.
Biruk Mosisa GudetaDepartment of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.
Belayneh Kefale GelawDepartment of Pharmacy, College of Medicine and Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0000-0003-4841-0861
Ambo University · ETBule Hora University · ETDebre Tabor University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStroke is becoming a leading cause of death and adult disability in the developing world.

objectiveThe objective of the study was to assess the clinical characteristics, treatment outcomes, and its predictors among stroke patients admitted to Ambo University Referral Hospital (AURH), West Ethiopia.

methodsAll 111 stroke patients hospitalized from April 2016 to May 2019 were included using a hospital-based retrospective study. Socio-demographic profile, past medication history, clinical presentation, drugs prescribed for comorbid condition and stroke treatment, and outcomes data were collected using data abstraction formats and results were summarized using both descriptive and inferential statistics. KEY

findingsAccording to WHO clinical criteria, 89 (80.2%) were diagnosed with ischemic stroke, and 20 (18.0%) were diagnosed with hemorrhagic stroke. The majority of the patients 94 (84.7%) had at least one antecedent risk factor in which hypertension accounted for 44.1%. More than half, 69 (62.2%), of hospitalized stroke patients had good treatment outcomes while 42 (37.8%) had a poor outcome. The overall case-fatality rate was 18 (16.2%), 12 (13.5%) from ischemic stroke, and 6 (30.0%) from hemorrhagic stroke. Acetyl salicylic acid (ASA) with atorvastatin/simvastatin, 67 (73.5%) in ischemic stroke and 12 (60.0%) in hemorrhagic stroke, was the most frequent medications prescribed for stroke during admission while it was frequently prescribed for 48 (53.6%) of ischemic stroke and 10 (50.0%) of the hemorrhagic stroke on discharge. Overall, ceftriaxone + metronidazole 32 (28.8%) was frequently prescribed concomitant medications during admission. The major predictors identified for poor stroke outcomes were substance abuse (AOR=2.839, P=0.024) and have had not received any medication for stroke treatment during admission (AOR=12.503, P≤0.001).

conclusionA significant number of the admitted stroke patients had poor treatment outcome in which the case-fatality rate was relatively high. Substance abuse and having not received medication for stroke were the significant predictors for poor treatment outcome. Hence, a well-established stroke unit setup at AURH is required for accurate diagnosis and management of stroke to overcome stroke-related mortality and/or poor treatment outcome.

Indexed as

HospitalizationHospitals, UniversityAgedEthiopiaFemaleHemorrhagic StrokeHumansIschemic StrokeMaleMiddle AgedRetrospective StudiesTreatment OutcomeAmboEthiopiaoutcomespredictorsstroke

Identifiers

PMID33447039
PMCPMC7802015
OpenAlexW3118669409

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.