Evidence map›Paper›PMID 33447028›Full record

ArticleInternational journal of nanomedicine2021

DPPG

F Johannes P van Valenberg, Iris S G Brummelhuis, Lars H Lindner, Felix Kuhnle, Barbara Wedmann, Pascal Schweizer, Martin Hossann, J Alfred Witjes, Egbert Oosterwijk

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Heat-activated intravenous liposomal doxorubicin combined with mitomycin C hyperthermic intravesical chemotherapy (HIVEC) for treatment of bladder cancer.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

F Johannes P van Valenberg *Department of Urology, Radboud University Medical Center, Nijmegen, the Netherlands.ORCID 0000-0003-1663-1192
Iris S G Brummelhuis *Department of Urology, Radboud University Medical Center, Nijmegen, the Netherlands.ORCID 0000-0003-2016-3790
Lars H LindnerDepartment of Medicine III, University Hospital LMU Munich, Munich, Germany.ORCID 0000-0003-3708-8264
Felix KuhnleDepartment of Medicine III, University Hospital LMU Munich, Munich, Germany.
Barbara WedmannDepartment of Medicine III, University Hospital LMU Munich, Munich, Germany.
Pascal SchweizerThermosome GmbH, Munich, Germany.ORCID 0000-0002-3900-4477
Martin HossannThermosome GmbH, Munich, Germany.ORCID 0000-0002-7592-5919
J Alfred WitjesDepartment of Urology, Radboud University Medical Center, Nijmegen, the Netherlands.
Egbert OosterwijkDepartment of Urology, Radboud University Medical Center, Nijmegen, the Netherlands.
Radboud University Nijmegen · NLLMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCurrent treatment options for muscle-invasive bladder cancer (MIBC) are associated with substantial morbidity. Local release of doxorubicin (DOX) from phosphatidyldiglycerol-based thermosensitive liposomes (DPPG MATERIALS AND

methodsTwenty-one pigs were anaesthetized, and a urinary catheter equipped with a radiofrequency-emitting antenna for HT (60 minutes) was placed. Experimental groups consisted of iv low or full dose (20 or 60 mg/m

resultsIv DPPG

conclusionIv DPPG

Indexed as

Hyperthermia, InducedAnimalsAntibiotics, AntineoplasticCell Line, TumorDoxorubicinDrug Delivery SystemsFemaleFluorescenceHumansLiposomesMusclesNeoplasm InvasivenessPhosphatidylglycerolsSwineTemperatureUrinary Bladder Neoplasms1,2-dipalmitoylphosphatidylglycerolAntibiotics, AntineoplasticDoxorubicinLiposomesPhosphatidylglycerolschemotherapeuticdrug delivery systemlocal releaseMIBCporcine modeltherapy

Identifiers

PMID33447028
PMCPMC7802347
OpenAlexW3120547681

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.