Evidence map›Paper›PMID 33446836›Full record

ArticleScientific reports2021

The association between bowel resection and the risk of nontyphoidal salmonella infection: a nationwide propensity score-matched cohort study.

Kuang-Tsu Yang, Sin-Ei Juang, Yao-Min Hung, James Cheng-Chung Wei, Hei-Tung Yip, Renin Chang

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Kuang-Tsu YangDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan (R.O.C.).
Sin-Ei JuangDepartment of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan (R.O.C.).
Yao-Min HungDepartment of Internal Medicine, Kaohsiung Municipal United Hospital, Kaohsiung, Taiwan (R.O.C.).
James Cheng-Chung WeiGraduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan (R.O.C.).
Hei-Tung YipManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan (R.O.C.).
Renin ChangDepartment of Emergency Medicine, Kaohsiung Veterans General Hospital, No. 386, Dazhong 1st Rd., Zuoying Dist., Kaohsiung City, 813414, Taiwan (R.O.C.). rhapsody1881@gmail.com.
China Medical University · TWKaohsiung Chang Gung Memorial Hospital · TWKaohsiung Municipal Hsiao-Kang Hospital · TWKaohsiung Veterans General Hospital · TWTajen University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nontyphoidal salmonella (NTS) infection has a high mortality rate. Bowel resections affect gut microbiota and immune function, and the association between bowel resection and NTS infection in human beings has not been addressed. We conducted a nationwide propensity score (PS)-matched cohort study to clarify this association. Data from the Longitudinal Health Insurance Database of Taiwan were used to establish a case-cohort with bowel resections from 2000 to 2013. Informed consent was waived by the Institutional Review Board of China Medical University Hospital (CMUH104-REC2-115) because all personal identifying information used had been de-identified. Each case was matched with one control without any bowel resection according to age, gender, index date, and propensity score (PS). Cumulative incidences of and hazard ratios (HRs) for NTS infection development were analyzed. The incidence of NTS infection was greater in patients with a bowel resection than in the control group (2.97 vs. 1.92 per 10,000 person-years), with an adjusted hazard ratio (aHR) of 1.64 (95% CI = 1.08-2.48). The incidence of NTS infection increased significantly for cases with small bowel resections and right hemicolectomies. Age (31-40 and > 50 years), hypertension, chronic kidney disease, chronic obstructive pulmonary disease, and autoimmune diseases were significant risk factors of NTS infection. Stratification analysis revealed that patients without comorbidities were prone to NTS infection after bowel resections. The increased risk of developing NTS infection could be related to the bowel resection. Specific age groups and comorbidities also contribute to increased risk of NTS infection.

Indexed as

Databases, FactualIntestine, SmallPostoperative ComplicationsSalmonella InfectionsAdolescentAdultDigestive System Surgical ProceduresFemaleHumansIncidenceMaleMiddle AgedTaiwan

Identifiers

PMID33446836
PMCPMC7809203
OpenAlexW3121417213

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.