Evidence map›Paper›PMID 33446147›Full record

ArticleBMC cancer2021

Evaluation of

Manuel Weber, Walter Jentzen, Regina Hofferber, Ken Herrmann, Wolfgang Peter Fendler, Christoph Rischpler, Lale Umutlu, Maurizio Conti, Pedro Fragoso Costa, Miriam Sraieb and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Time to shift to Digital PET/CT?Nuclear medicine and molecular imaging · 2025
    Article
  2. Staging of prostate Cancer with ultra-fast PSMA-PET scans enhanced by AI.European journal of nuclear medicine and molecular imaging · 2025
    Article
  3. LowQuantitative imaging in medicine and surgery · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Lesion Quantification Accuracy of DigitalJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  9. Article
  10. Artificial intelligence guided enhancement of digital PET: scans as fast as CT?European journal of nuclear medicine and molecular imaging · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. New PET technologies - embracing progress and pushing the limits.European journal of nuclear medicine and molecular imaging · 2021
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Manuel WeberDepartment of Nuclear Medicine, University of Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany. manuel.weber@uk-essen.de.
Walter JentzenDepartment of Nuclear Medicine, University of Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Regina HofferberDepartment of Nuclear Medicine, University of Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Ken HerrmannDepartment of Nuclear Medicine, University of Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Wolfgang Peter FendlerDepartment of Nuclear Medicine, University of Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Christoph RischplerDepartment of Nuclear Medicine, University of Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Lale UmutluUniversity of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital, Essen, Germany.
Maurizio ContiSiemens Medical Solutions USA, INC, Erlangen, Germany.
Pedro Fragoso CostaDepartment of Nuclear Medicine, University of Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Miriam SraiebDepartment of Nuclear Medicine, University of Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
David KerstingDepartment of Nuclear Medicine, University of Duisburg-Essen, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Deutschen Konsortium für Translationale Krebsforschung · DEUniversity of Duisburg-Essen · DEEssen University Hospital · DESiemens (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe superior accuracy and sensitivity of

methodsTwenty patients with (suspected) lymphoma (6 for initial staging, 12 after systemic treatment, 2 in suspicion of recurrence) sequentially underwent

resultsAll defined regions were correctly classified in the images acquired with reduced emission time, and therefore, no changes in staging were observed. Lesion quantification was acceptable, that is, mean absolute percentage deviation of maximum and peak standardized uptake values were 6.8 and 6.4% (derived from 30 lesions). A threefold reduction of scan time duration led to an increase in image noise from 7.1 to 11.0% (images reconstructed with 4 iterations) and from 4.7 to 7.2% (images reconstructed with 2 iterations). No deviations in Deauville Score were observed.

conclusionThese results suggest that scan time duration or administered tracer activity can be reduced threefold without compromising diagnostic performance. Especially a reduction of administered activity might allow for a lower radiation exposure and better health economics. Larger trials are warranted to confirm our results.

Indexed as

AdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18Follow-Up StudiesHumansImage Processing, Computer-AssistedLymphomaMaleMiddle AgedPositron Emission Tomography Computed TomographyPrognosisRadiopharmaceuticalsRetrospective StudiesYoung AdultFluorodeoxyglucose F18RadiopharmaceuticalsFDGImage qualityLymphomaPET/CTSilicon photomultiplier

Identifiers

PMID33446147
PMCPMC7807699
OpenAlexW3118437775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.