Evidence map›Paper›PMID 33446027›Full record

ArticleAIDS research and human retroviruses2021

Simian Immunodeficiency Virus Susceptibility, Immunology, and Microbiome in the Female Genital Tract of Adolescent Versus Adult Pigtail Macaques.

Alicia R Berard, Charlene Miller, Mariluz Araínga, Courtney Ann Broedlow, Laura Noël-Romas, Luca Schifanella, Tiffany Hensley-McBain, Alex Roederer, Connor B Driscoll, Ernesto Coronado and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS research and human retroviruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Microbiome Studies in Non-human Primates.Current HIV/AIDS reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 4 countries.

Alicia R BerardDepartment of Obstetrics & Gynecology, University of Manitoba, Winnipeg, Canada.
Charlene MillerDepartment of Pediatrics, University of Miami, Miami, Florida, USA.
Mariluz AraíngaNew Iberia Research Center, University of Louisiana at Lafayette, New Iberia, Louisiana, USA.
Courtney Ann BroedlowDepartment of Pediatrics, University of Miami, Miami, Florida, USA.
Laura Noël-RomasDepartment of Obstetrics & Gynecology, University of Manitoba, Winnipeg, Canada.
Luca SchifanellaDivision of Surgical Outcomes and Precision Medicine Research, Department of Surgery, University of Minnesota, Minneapolis, Minnesota, USA.
Tiffany Hensley-McBainDepartment of Pediatrics, University of Miami, Miami, Florida, USA.
Alex RoedererDepartment of Pharmaceutics, University of Washington, Seattle, Washington, USA.
Connor B DriscollDepartment of Pediatrics, University of Miami, Miami, Florida, USA.
Ernesto CoronadoDepartment of Pharmaceutics, University of Washington, Seattle, Washington, USA.
Jennifer ManuzakDepartment of Pediatrics, University of Miami, Miami, Florida, USA.
Lyle R McKinnonDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada.
Francois VillingerNew Iberia Research Center, University of Louisiana at Lafayette, New Iberia, Louisiana, USA.
Thomas J HopeDepartment of Cell & Molecular Biology, Northwestern University, Chicago, Illinois, USA.
Adam D BurgenerDepartment of Obstetrics & Gynecology, University of Manitoba, Winnipeg, Canada.
Nichole R KlattDepartment of Pediatrics, University of Miami, Miami, Florida, USA.
University of Miami · USUniversity of Manitoba · CAUniversity of Washington · USUniversity of Louisiana at Lafayette · USCenter for Global Health · USNorthwestern University · USUniversity of Minnesota · US

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Virus TransmissionP50AI150464 · NIAID · UNIVERSITY OF UTAH · PI KAY, MICHAEL S · 2019 to 2021
$14.9M
Mucosal mechanisms of altered HIV susceptibility in adolescentsR01AI128782 · NIAID · UNIVERSITY OF WASHINGTON · PI BURGENER, ADAM, HOPE, THOMAS · 2017 to 2020
$2.5M
Impact of Malaria Co-Infection on HIV VaccinationK01OD024876 · OD · UNIVERSITY OF WASHINGTON · PI MANUZAK, JENNIFER · 2017 to 2019
$1.0M
NIAID NIH HHS P50 AI150464NIAID NIH HHS R01 AI128782NIH HHS K01 OD024876NIH HHS P51 OD011104
6 · The paper itself

Abstract

In Sub-Saharan Africa, young women 15-24 years of age account for nearly 30% of all new HIV infections, however, biological and epidemiological factors underlying this disproportionate infection rate are unclear. In this study, we assessed biological contributors of SIV/HIV susceptibility in the female genital tract (FGT) using adolescent (

Indexed as

HIV InfectionsMicrobiotaSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAdolescentAdultAnimalsFemaleGenitalia, FemaleHumansMacaca nemestrinaProteomicsRNA, Ribosomal, 16SRNA, Ribosomal, 16Sadolescent femalesnon-human primatepigtail macaquesimian immunodeficiency virus (SIV)translational researchvaginal microbiomevaginal transmission

Identifiers

PMID33446027
PMCPMC8260895
OpenAlexW3123552445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.