Evidence map›Paper›PMID 33445645›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Quantitative Evaluation of Fibrosis in IPF Patients: Meaning of Diffuse Pulmonary Ossification.

Monica Palermo, Francesco Tiralongo, Giulio Distefano, Ada Vancheri, Mauro Giuffrè, Fabio Pino, Pietro Valerio Foti, Gianluca Sambataro, Carlo Vancheri, Stefano Palmucci and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Pulmonary ossification: a review.Journal of thoracic disease · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Monica PalermoRadiology Unit 1, Department of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.ORCID 0000-0003-0826-2235
Francesco TiralongoRadiology Unit 1, Department of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.ORCID 0000-0001-9637-1970
Giulio DistefanoRadiology Unit 1, Department of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.ORCID 0000-0003-0735-5720
Ada VancheriRegional Referral Centre for Rare Lung Diseases, Department of Clinical and Experimental Medicine, University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.
Mauro GiuffrèDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34151 Trieste, Italy.ORCID 0000-0002-9910-3514
Fabio PinoRegional Referral Centre for Rare Lung Diseases, Department of Clinical and Experimental Medicine, University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.
Pietro Valerio FotiRadiology Unit 1, Department of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.
Gianluca SambataroRegional Referral Centre for Rare Lung Diseases, Department of Clinical and Experimental Medicine, University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.ORCID 0000-0001-9933-1202
Carlo VancheriRegional Referral Centre for Rare Lung Diseases, Department of Clinical and Experimental Medicine, University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.
Stefano PalmucciRadiology Unit 1, Department of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.ORCID 0000-0002-7196-2974
Antonio BasileRadiology Unit 1, Department of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University-Hospital Policlinico "G. Rodolico-S. Marco", University of Catania, 95123 Catania, Italy.
University of Catania · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the role of diffuse pulmonary ossification (DPO) in disease severity in a population of Idiopathic Pulmonary Fibrosis (IPF) patients. This retrospective study was carried out on 95 IPF patients-44 with DPO on high resolution computed tomography (HRCT) and 51 with no calcifications detected on HRCT. Pulmonary Function Tests (PFTs) acquired nearest to the HRCT were collected. Images were analyzed by two radiologists using a qualitative method, based on HRCT fibrosis visual score, and using a quantitative method, based on histogram-based analysis. The Spearman's rank correlation coefficient was used to measure the strength and direction of the linear relationship between HRCT fibrosis score and PFTs; in addition, Spearman's rank correlation coefficient was used to explore the relationships between HRCT fibrosis score and quantitative index and between quantitative indexes and PFTs. A weak correlation between HRCT fibrosis score and PFTs was proven (r =-0.014 and

Indexed as

fibrosishistogram-based analysisHRCTinterstitial lung diseasesIPFkurtosislung diseasespulmonary ossificationquantificationvisual score

Identifiers

PMID33445645
PMCPMC7828113
OpenAlexW3119441099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.