Evidence map›Paper›PMID 33445642›Full record

ArticleCancers2021

Epigenetic Modulation of SPCA2 Reverses Epithelial to Mesenchymal Transition in Breast Cancer Cells.

Monish Ram Makena, Myungjun Ko, Donna Kimberly Dang, Rajini Rao

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Wnt/CaOncology letters · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Expression and associated epigenetic mechanisms of the CaJournal of cell communication and signaling · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Monish Ram MakenaDepartment of Physiology, Johns Hopkins University School of Medicine, 725 N. Wolfe St, Baltimore, MD 21205, USA.ORCID 0000-0002-4068-7375
Myungjun KoDepartment of Physiology, Johns Hopkins University School of Medicine, 725 N. Wolfe St, Baltimore, MD 21205, USA.ORCID 0000-0003-4330-1324
Donna Kimberly DangDepartment of Physiology, Johns Hopkins University School of Medicine, 725 N. Wolfe St, Baltimore, MD 21205, USA.
Rajini RaoDepartment of Physiology, Johns Hopkins University School of Medicine, 725 N. Wolfe St, Baltimore, MD 21205, USA.ORCID 0000-0002-1833-5971
Johns Hopkins University · US

Funding

Transport Mechanism and Renal Function of a Newly Recognized Na+/H+ ExchangerR01DK108304 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI RAO, RAJINI · 2015 to 2019
$2.3M
BSF 13044NIH/NIDDK R01DK108304
6 · The paper itself

Abstract

The secretory pathway Ca

Indexed as

Ca2+-ATPaseEMTHDAC inhibitorsromidepsinSICETNBCvimentinvorinostatWNT signaling

Identifiers

PMID33445642
PMCPMC7827456
OpenAlexW3120959786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.