Evidence map›Paper›PMID 33445569›Full record

ReviewCells2021

Double Duty: Mitotic Kinesins and Their Post-Mitotic Functions in Neurons.

Nadine F Joseph, Supriya Swarnkar, Sathyanarayanan V Puthanveettil

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Non-transport functions of motor proteins in corticogenesis.Frontiers in cell and developmental biology · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Axonal transport deficits in neuropsychiatric disorders.Molecular and cellular neurosciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nadine F JosephThe Skaggs Graduate School of Chemical and Biological Sciences, Scripps Research Institute, La Jolla, CA 92037, USA.
Supriya SwarnkarDepartment of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA.ORCID 0000-0001-7596-0215
Sathyanarayanan V PuthanveettilDepartment of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA.
Scripps Research Institute · US

Funding

Axonal Transport and Long-Term Memory StorageR01MH094607 · NIMH · SCRIPPS FLORIDA · PI PUTHANVEETTIL, SATHYA · 2014 to 2018
$2.3M
Molecular Substrates of Translation in Specific Neuronal Compartments During Memory StorageR21MH108929 · NIMH · SCRIPPS FLORIDA · PI PUTHANVEETTIL, SATHYA · 2015 to 2016
$528k
NIMH NIH HHS R01 MH094607NIMH NIH HHS R21 MH108929
6 · The paper itself

Abstract

Neurons, regarded as post-mitotic cells, are characterized by their extensive dendritic and axonal arborization. This unique architecture imposes challenges to how to supply materials required at distal neuronal components. Kinesins are molecular motor proteins that mediate the active delivery of cellular materials along the microtubule cytoskeleton for facilitating the local biochemical and structural changes at the synapse. Recent studies have made intriguing observations that some kinesins that function during neuronal mitosis also have a critical role in post-mitotic neurons. However, we know very little about the function and regulation of such kinesins. Here, we summarize the known cellular and biochemical functions of mitotic kinesins in post-mitotic neurons.

Indexed as

MitosisAnimalsHumansKinesinsMicrotubulesModels, BiologicalNeuronal PlasticityNeuronsKinesinscancerkinesinsmicrotubule regulationmitosisstructural plasticitysynaptic plasticitytransport

Identifiers

PMID33445569
PMCPMC7827351
OpenAlexW3120061315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.