Evidence map›Paper›PMID 33445436›Full record

ArticleSensors (Basel, Switzerland)2021

Vacuum Ultraviolet Absorption Spectroscopy Analysis of Breath Acetone Using a Hollow Optical Fiber Gas Cell.

Yudai Kudo, Saiko Kino, Yuji Matsuura

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yudai KudoGraduate School of Biomedical Engineering, Tohoku University, 6-6-05 Aoba, Sendai 980-8579, Japan.
Saiko KinoGraduate School of Biomedical Engineering, Tohoku University, 6-6-05 Aoba, Sendai 980-8579, Japan.
Yuji MatsuuraGraduate School of Biomedical Engineering, Tohoku University, 6-6-05 Aoba, Sendai 980-8579, Japan.ORCID 0000-0002-4722-7654
Tohoku University · JP

Funding

Japan Society for the Promotion of Science JP 20H00231Japan Society for the Promotion of Science JP 20K12615
6 · The paper itself

Abstract

Human breath is a biomarker of body fat metabolism and can be used to diagnose various diseases, such as diabetes. As such, in this paper, a vacuum ultraviolet (VUV) spectroscopy system is proposed to measure the acetone in exhaled human breath. A strong absorption acetone peak at 195 nm is detected using a simple system consisting of a deuterium lamp source, a hollow-core fiber gas cell, and a fiber-coupled compact spectrometer corresponding to the VUV region. The hollow-core fiber functions both as a long-path and an extremely small-volume gas cell; it enables us to sensitively measure the trace components of exhaled breath. For breath analysis, we apply multiple regression analysis using the absorption spectra of oxygen, water, and acetone standard gas as explanatory variables to quantitate the concentration of acetone in breath. Based on human breath, we apply the standard addition method to obtain the measurement accuracy. The results suggest that the standard deviation is 0.074 ppm for healthy human breath with an acetone concentration of around 0.8 ppm and a precision of 0.026 ppm. We also monitor body fat burn based on breath acetone and confirm that breath acetone increases after exercise because it is a volatile byproduct of lipolysis.

Indexed as

AcetoneAdipose TissueBreath TestsEquipment DesignExerciseHealthy VolunteersHumansMonitoring, PhysiologicOptical FibersRegression AnalysisSensitivity and SpecificitySpectrophotometry, UltravioletVacuumVolatile Organic CompoundsYoung AdultAcetoneVolatile Organic Compoundsbreath acetone measurementhollow optical fibervacuum ultraviolet spectroscopy

Identifiers

PMID33445436
PMCPMC7827082
OpenAlexW3120153560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.