Evidence map›Paper›PMID 33445313›Full record

ArticleACS biomaterials science & engineering2018

Electroconductive Gelatin Methacryloyl-PEDOT:PSS Composite Hydrogels: Design, Synthesis, and Properties.

Andrew R Spencer, Asel Primbetova, Abigail N Koppes, Ryan A Koppes, Hicham Fenniri, Nasim Annabi

Open access · greenAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 116 citations in OpenAlex.

  1. Article
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  6. PEDOT:PSS-A Key Material for Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
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  9. Article
  10. Article
  11. Article
  12. RSC advances · 2025
    Article
  13. Article
  14. Review
  15. Electrically conductive "SMART" hydrogels for on-demand drug delivery.Asian journal of pharmaceutical sciences · 2025
    Review
  16. Review
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrew R Spencer
Asel Primbetova
Abigail N Koppes
Ryan A Koppes
Nasim AnnabiBiomaterials Innovation Research Center, Brigham and Women's Hospital, Harvard Medical School, 65 Landsdowne Street, Boston, Massachusetts 02139, United States.
Northeastern University · USBrigham and Women's Hospital · US

Funding

Engineering highly elastic surgical sealants with hemostatic propertiesR01HL140618 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANNABI, NASIM, KHADEMHOSSEINI, ALI · 2018 to 2021
$2.8M
Engineering a naturally derived and highly adhesive surgical sealantR01EB023052 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANNABI, NASIM, KHADEMHOSSEINI, ALI · 2017 to 2022
$2.4M
American Heart Association-American Stroke Association 16SDG31280010NHLBI NIH HHS R01 HL140618NIBIB NIH HHS R01 EB023052
6 · The paper itself

Abstract

Electroconductive hydrogels are used in a wide range of biomedical applications, including electrodes for patient monitoring and electrotherapy, or as biosensors and electrochemical actuators. Approaches to design electroconductive hydrogels are often met with low biocompatibility and biodegradability, limiting their potential applications as biomaterials. In this study, composite hydrogels were prepared from a conducting polymer complex, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) dispersed within a photo-crosslinkable naturally derived hydrogel, gelatin methacryloyl (GelMA). To determine the impact of PEDOT:PSS loading on physical and microstructural properties and cellular responses, the electrical and mechanical properties, electrical properties, and biocompatibility of hydrogels loaded with 0-0.3% (w/v) PEDOT:PSS were evaluated and compared to GelMA control. Our results indicated that the properties of the hydrogels, such as mechanics, degradation, and swelling, could be tuned by changing the concentration of PEDOT:PSS. In particular, the impedance of hydrogels decreased from 449.0 kOhm for control GelMA to 281.2 and 261.0 kOhm for hydrogels containing 0.1% (w/v) and 0.3% (w/v) PEDOT:PSS at 1 Hz frequency, respectively. In addition, an

Indexed as

compositeconductive polymerelectroconductivegelatinhydrogelPEDOT:PSS

Identifiers

PMID33445313
PMCPMC11150039
OpenAlexW2793539539

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.