Evidence map›Paper›PMID 33445071›Full record

ArticleDiabetes & metabolic syndrome

Clinical characteristics and outcomes of COVID-19 infected diabetic patients admitted in ICUs of the southern region of Bangladesh.

Ayan Saha, Mohammed Moinul Ahsan, Md Tarek-Ul Quader, Sabekun Naher, Farhana Akter, H M Hamidullah Mehedi, Asm Arman Ullah Chowdhury, Md Hasanul Karim, Tazrina Rahman, Ayesha Parvin

Open access · greenAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes & metabolic syndrome. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ayan SahaChildren's Cancer Institute, Faculty of Medicine, University of New South Wales, Australia; Disease Biology and Molecular Epidemiology Research Group, Chattogram, 4000, Bangladesh. Electronic address: ayan.saha.bd@gmail.com.
Mohammed Moinul AhsanIntensive Care Unit, 250 Bedded General Hospital, Chattogram, 4000, Bangladesh.
Md Tarek-Ul QuaderDepartment of Anesthesiology and Intensive Care Unit, Chittagong Medical College, Chattogram, 4202, Bangladesh.
Sabekun NaherDepartment of Microbiology, University of Chittagong, Chattogram, 4202, Bangladesh.
Farhana AkterDepartment of Endocrinology, Chittagong Medical College, Chattogram, 4202, Bangladesh; Disease Biology and Molecular Epidemiology Research Group, Chattogram, 4000, Bangladesh.
H M Hamidullah MehediDepartment of Medicine, 250 Bedded General Hospital, Chattogram, 4000, Bangladesh.
Asm Arman Ullah ChowdhuryIntensive Care Unit, 250 Bedded General Hospital, Chattogram, 4000, Bangladesh.
Md Hasanul KarimIntensive Care Unit, 250 Bedded General Hospital, Chattogram, 4000, Bangladesh.
Tazrina RahmanDepartment of Microbiology and Virology, Chittagong Medical College, Chattogram, 4202, Bangladesh.
Ayesha ParvinDepartment of Biochemistry, Chittagong Medical College, Chattogram, 4202, Bangladesh.
Chittagong Medical College · BDUniversity of Chittagong · BDUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsDiabetes mellitus is highly prevalent among critical cases of coronavirus disease 2019 (COVID-19) with poor outcomes. This study aimed to describe the clinical characteristics and outcomes of COVID-19 patients with diabetes, admitted in the intensive care unit (ICU) of the southern region of Bangladesh.

methodsEpidemiological, clinical, laboratory, treatments, complications, and clinical outcomes data were extracted from electronic medical records of 168 COVID-19 patients admitted into ICU of two COVID-19 dedicated hospitals of Chattogram, Bangladesh and compared between diabetes (n = 88) and non-diabetes (n = 80) groups.

resultsThe prevalence of diabetes was high among 51-70 years old patients. All the diabetic patients had at least one other comorbidity, with a significantly higher incidence of hypertension (53.4% vs 27.5%, P < 0.05). Prevalence of male patients (74/88; 84.1%) was slightly higher among diabetic patients than the non-diabetic patients (60/80; 75%). Even though not significant, Kaplan-Meier survival curve showed that COVID-19 patients with diabetes had a shorter overall survival time than those without diabetes. In subgroup analysis, diabetic patients were classified into insulin-requiring and non-insulin-requiring groups based on their requirement of insulin during the stay in ICU. COVID-19 infected diabetic patients requiring insulin have high risk of disease progression and shorter survival time than the non-insulin required group.

conclusionsDiabetes is an independent risk factor for the poor prognosis of COVID-19. More attention should be paid to the prevention and prompt treatment of diabetic patients, to maintain good glycaemic control especially those who require insulin therapy.

Indexed as

AdolescentAdultAgedAged, 80 and overBangladeshChildCohort StudiesCOVID-19Diabetes MellitusFemaleHumansHypertensionIntensive Care UnitsMaleMiddle AgedPatient AdmissionBangladeshClinical characteristicsCOVID-19Diabetes mellitusEpidemiology

Identifiers

PMID33445071
PMCPMC7837249
OpenAlexW3114738512

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.