Evidence map›Paper›PMID 33444709›Full record

ArticleJournal of the American College of Surgeons2021

Racial Disparity in Liver Transplantation Listing.

Curtis Warren, Anne-Marie Carpenter, Daniel Neal, Kenneth Andreoni, George Sarosi, Ali Zarrinpar

Open access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal of the American College of Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Exploring Disease-Specific Waitlist Outcomes in Simultaneous Liver-Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  7. Access to early liver transplantation is adversely impacted by social determinants of health: A retrospective cohort study.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2025
    Article
  8. Article
  9. Racial and ethnic disparities in liver transplant access vary within and across transplant referral regions.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Waiting for a Liver Transplant in New Mexico; Understanding the State's Multi-layered Adversity.Journal of community hospital internal medicine perspectives · 2024
    Article
  17. Review
  18. Article
  19. Identifying and understanding variation in population-based access to liver transplantation in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  20. Actionable Solutions to Achieve Health Equity in Chronic Liver Disease.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Curtis WarrenDepartment of Surgery, University of Florida, Gainesville, FL.
Anne-Marie CarpenterDepartment of Surgery, University of Florida, Gainesville, FL.
Daniel NealDepartment of Surgery, University of Florida, Gainesville, FL.
Kenneth AndreoniDepartment of Surgery, University of Florida, Gainesville, FL.
George SarosiDepartment of Surgery, University of Florida, Gainesville, FL.
Ali ZarrinparDepartment of Surgery, University of Florida, Gainesville, FL. Electronic address: Ali.Zarrinpar@surgery.ufl.edu.
University of Florida · US

Funding

Novel pathways in the pathogenesis and pathophysiology of NAFLD in HispanicsR01MD012579 · NIMHD · OHIO UNIVERSITY ATHENS · PI FRIEDMAN, THEODORE C, NAJJAR, SONIA M. · 2019 to 2023
$3.2M
Ischemia-reperfusion injury in liver transplantationK08DK113244 · NIDDK · UNIVERSITY OF FLORIDA · PI ZARRINPAR, ALI · 2017 to 2021
$814k
NIDDK NIH HHS K08 DK113244NIMHD NIH HHS R01 MD012579
6 · The paper itself

Abstract

backgroundPrevious studies have demonstrated disparities in transplantation for women, non-Caucasians, the uninsured or publicly insured, and rural populations. We sought to correlate transplant center characteristics with patient access to the waiting list and liver transplantation. We hypothesized that liver transplant centers vary greatly in providing equitable access to the waiting list and liver transplantation. STUDY

designCenter-specific, adult, deceased-donor liver transplant and waitlist data for the years 2013 to 2018 were obtained from the United Network for Organ Sharing. Waitlist race/ethnicity distributions from liver transplant centers performing ≥ 250 transplants over this period (n = 109) were compared with those of their donor service area, as calculated from 5-year US Census Bureau estimates of 2017. Center-specific characteristics correlating with disparities were analyzed using a linear regression model with a log transformed outcome.

resultsNon-Hispanic Blacks (NHBs) are under-represented in liver transplant listing compared with center donation service area (88/109, 81%), whereas, non-Hispanic Whites are over-represented (65/109, 58%) (p < 0.0001). Hispanics were also under-represented on the waitlist at the majority of transplant centers (68/109, 62%) (p = 0.02). Although the racial/ethnic distribution of transplantation is more reflective of the waitlist, there is a higher than expected rate of transplantation for NHBs compared to the waitlist. Predictors of disparity in listing include percentage of transplant recipients at the center who had private insurance, racial composition of the donation service area, and the distance recipients had to travel for transplant.

conclusionsNon-Hispanic Blacks are listed for liver transplantation less than would be expected. Once listed, however, racial disparities in transplantation are greatly diminished. Improvements in access to adequate health insurance appear to be essential to diminishing disparities in access to this life-saving care.

Indexed as

Black or African AmericanBlack PeopleEducational StatusEnd Stage Liver DiseaseFemaleHealthcare DisparitiesHealth Services AccessibilityHispanic or LatinoHumansInsurance CoverageLiver TransplantationMaleMiddle AgedSeverity of Illness IndexUnited StatesWaiting Lists

Identifiers

PMID33444709
PMCPMC8143858
OpenAlexW3120518670

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.