Evidence map›Paper›PMID 33444648›Full record

ArticleBiochimica et biophysica acta. Molecular cell research2021

UBXN7 cofactor of CRL3

Jacopo Di Gregorio, Lucia Cilenti, Camilla T Ambivero, Thomas Andl, Ronglih Liao, Antonis S Zervos

Open access · greenAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Molecular cell research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Ubiquitination and Metabolic Disease.Advances in experimental medicine and biology · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Regulation of Metabolism by Mitochondrial MUL1 E3 Ubiquitin Ligase.Frontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jacopo Di GregorioBurnett School of Biomedical Sciences, University of Central Florida College of Medicine, 12722 Research Parkway Orlando, FL 32826, United States of America.
Lucia CilentiBurnett School of Biomedical Sciences, University of Central Florida College of Medicine, 12722 Research Parkway Orlando, FL 32826, United States of America.
Camilla T AmbiveroBurnett School of Biomedical Sciences, University of Central Florida College of Medicine, 12722 Research Parkway Orlando, FL 32826, United States of America.
Thomas AndlBurnett School of Biomedical Sciences, University of Central Florida College of Medicine, 12722 Research Parkway Orlando, FL 32826, United States of America.
Ronglih LiaoStanford Cardiovascular Institute, Stanford University School of Medicine, 1651 Page Mill Road, Palo Alto, CA 94043, United States of America.
Antonis S ZervosBurnett School of Biomedical Sciences, University of Central Florida College of Medicine, 12722 Research Parkway Orlando, FL 32826, United States of America. Electronic address: Antonis.Zervos@ucf.edu.
University of Central Florida · USCardiovascular Institute of the South · US

Funding

Mulan: a novel regulator of mitochondrial dynamics, mitophagy and heart functionR01HL132511 · NHLBI · STANFORD UNIVERSITY · PI LIAO, RONGLIH, ZERVOS, ANTONIS S · 2017 to 2020
$2.8M
NHLBI NIH HHS R01 HL132511
6 · The paper itself

Abstract

UBXN7 is a cofactor protein that provides a scaffold for both CRL3

Indexed as

Adaptor Proteins, Signal TransducingCell HypoxiaGene Expression RegulationGene Knockdown TechniquesGlycolysisHEK293 CellsHumansHypoxia-Inducible Factor 1, alpha SubunitKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2Oxidative PhosphorylationOxidative StressUbiquitin-Protein LigasesAdaptor Proteins, Signal TransducingHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitKEAP1 protein, humanKelch-Like ECH-Associated Protein 1MUL1 protein, humanNFE2L2 protein, humanNF-E2-Related Factor 2Ubiquitin-Protein LigasesUBXN7 protein, humanGlycolysisHIF-1αMUL1NRF2Oxidative stressUBXN7

Identifiers

PMID33444648
PMCPMC7882025
OpenAlexW3119905564

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.