ArticleIET systems biology2019
Rehabilitation of the Parkinson's tremor by using robust adaptive sliding mode controller: a simulation study.
Article in IET systems biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 15 citations in OpenAlex.
- Editorial: Advancing the Frontiers of Non-Invasive Neuromodulation in Research and Clinical Practice.Brain sciences · 2026Article
- A dynamical model for the basal ganglia-thalamo-cortical oscillatory activity and its implications in Parkinson's disease.Cognitive neurodynamics · 2021Article
- Sliding mode controller-observer pair for p53 pathway.IET systems biology · 2019Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the efficient methods in controlling the Parkinson's tremor is Deep Brain Stimulation (DBS) therapy. The stimulation of Basal Ganglia (BG) by DBS brings no feedback though the existence of feedback reduces the additional stimulatory signal delivered to the brain. So this study offers a new adaptive architecture of a closed-loop control system in which two areas of BG are stimulated simultaneously to decrease the following three indicators: hand tremor, the level of a delivered stimulation signal in the disease condition, and the level of a delivered stimulation signal in health condition to the disease condition. One area (STN: subthalamic nucleus) is stimulated with an adaptive sliding mode controller and the other area (GPi: Globus Pallidus internal) with partial state feedback controller. The simulation results of stimulating two areas of BG showed satisfactory performance.
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