Evidence map›Paper›PMID 33444414›Full record

ArticlePLoS pathogens2021

Short and sweet: How glycans impact prion conversion, cofactor interactions, and cross-species transmission.

Patricia Aguilar-Calvo, Julia A Callender, Christina J Sigurdson

Abstract read
In one paragraph

Article in PLoS pathogens, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Vaccines for prion diseases: a realistic goal?Cell and tissue research · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patricia Aguilar-CalvoDepartment of Pathology, University of California, San Diego, La Jolla, California, United States of America.
Julia A CallenderDepartment of Pathology, University of California, San Diego, La Jolla, California, United States of America.
Christina J SigurdsonDepartment of Pathology, University of California, San Diego, La Jolla, California, United States of America.ORCID 0000-0003-0166-9382

Funding

Mechanisms of Prion Aggregation and Species BarriersR01NS069566 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ESKO, JEFFREY D, RAVITS, JOHN · 2011 to 2025
$5.7M
UCSD Biomedical Scientist Career Development Program in GlycoscienceK12HL141956 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ESKO, JEFFREY D, GODULA, KAMIL · 2018 to 2022
$5.3M
Mechanisms of Prion SpreadR01NS076896 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2012 to 2021
$3.4M
Molecular basis of prion protein-induced neurodegenerationRF1NS121992 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2021 to 2023
$1.7M
Probing prion clearance through interstitial fluid and perivascular pathwaysR21NS110409 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2018 to 2019
$433k
Molecular basis of spongiform encephalopathy in prion diseaseR21NS105498 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2018 to 2019
$432k
Role of heparan sulfate in neural cell vulnerability to prionsK99AG061251 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AGUILAR CALVO, PATRICIA · 2019 to 2021
$375k
NHLBI NIH HHS K12 HL141956NIA NIH HHS K99 AG061251NINDS NIH HHS R01 NS069566NINDS NIH HHS R01 NS076896NINDS NIH HHS R21 NS105498NINDS NIH HHS R21 NS110409NINDS NIH HHS RF1 NS121992
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AmyloidAnimalsPolysaccharidesPrion DiseasesPrionsPrPC ProteinsSpecies SpecificityAmyloidPolysaccharidesPrionsPrPC Proteins

Identifiers

PMID33444414
PMCPMC7808606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.