Evidence map›Paper›PMID 33444218›Full record

ArticleBMJ open2020

Predicting dementia diagnosis from cognitive footprints in electronic health records: a case-control study protocol.

Hao Luo, Kui Kai Lau, Gloria H Y Wong, Wai-Chi Chan, Henry K F Mak, Qingpeng Zhang, Martin Knapp, Ian C K Wong

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Early prediction of Alzheimer's disease and related dementias using real-world electronic health records.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Hao LuoDepartment of Social Work and Social Administration, University of Hong Kong, Hong Kong, China haoluo@hku.hk.ORCID 0000-0003-4261-3414
Kui Kai LauDepartment of Medicine, University of Hong Kong, Hong Kong, China.
Gloria H Y WongDepartment of Social Work and Social Administration, University of Hong Kong, Hong Kong, China.ORCID 0000-0002-1331-942X
Wai-Chi ChanDepartment of Psychiatry, University of Hong Kong, Hong Kong, China.
Henry K F MakDepartment of Diagnostic Radiology, University of Hong Kong, Hong Kong, China.
Qingpeng ZhangSchool of Data Science, City University of Hong Kong, Hong Kong, China.
Martin KnappCare Policy and Evaluation Centre (CPEC), The London School of Economics and Political Science, London, UK.
Ian C K WongCentre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong, China.
University of Hong Kong · HKCity University of Hong Kong · HKLondon School of Economics and Political Science · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDementia is a group of disabling disorders that can be devastating for persons living with it and for their families. Data-informed decision-making strategies to identify individuals at high risk of dementia are essential to facilitate large-scale prevention and early intervention. This population-based case-control study aims to develop and validate a clinical algorithm for predicting dementia diagnosis, based on the cognitive footprint in personal and medical history. METHODS AND ANALYSIS: We will use territory-wide electronic health records from the Clinical Data Analysis and Reporting System (CDARS) in Hong Kong between 1 January 2001 and 31 December 2018. All individuals who were at least 65 years old by the end of 2018 will be identified from CDARS. A random sample of control individuals who did not receive any diagnosis of dementia will be matched with those who ETHICS AND DISSEMINATION: This study was approved by Institutional Review Board of The University of Hong Kong/Hospital Authority Hong Kong West Cluster (UW 18-225). Patients' records are anonymised to protect privacy. Study results will be disseminated through peer-reviewed publications. Codes of the resulted dementia risk prediction algorithm will be made publicly available at the website of the Tools to Inform Policy: Chinese Communities' Action in Response to Dementia project (https://www.tip-card.hku.hk/).

Indexed as

DementiaElectronic Health RecordsAdultAgedAged, 80 and overCase-Control StudiesCognitionFemaleHong KongHumansMaleMiddle Ageddementiaepidemiologypublic health

Identifiers

PMID33444218
PMCPMC7678375
OpenAlexW3098909529

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.