Evidence map›Paper›PMID 33444134›Full record

ArticleIEEE transactions on medical imaging2021

Generating Synthetic Labeled Data From Existing Anatomical Models: An Example With Echocardiography Segmentation.

Andrew Gilbert, Maciej Marciniak, Cristobal Rodero, Pablo Lamata, Eigil Samset, Kristin Mcleod

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  12. MRXCAT2.0: Synthesis of realistic numerical phantoms by combining left-ventricular shape learning, biophysical simulations and tissue texture generation.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  13. [Research progress on medical image dataset expansion methods].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Review
  14. An Overview of Deep Learning Methods for Left Ventricle Segmentation.Computational intelligence and neuroscience · 2023
    Review
  15. Echo from noise: synthetic ultrasound image generation using diffusion models for real image segmentation.Simplifying medical ultrasound : 4th International Workshop, ASMUS 2023, held in conjunction with MICCAI 2023, Vancouver, BC, Canada, October 8, 2023, Proceedings. ASMUS (Workshop) (4th : 2023 : Vancouver, B.C. ; Online) · 2023
    Article
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  17. Efficient Pix2Vox++ for 3D Cardiac Reconstruction from 2D echo views.Simplifying medical ultrasound : third International Workshop, ASMUS 2022, held in conjunction with MICCAI 2022, Singapore, September 18, 2022, Proceedings. ASMUS (Workshop) (3rd : 2022 : Singapore) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrew Gilbert
Maciej Marciniak
Cristobal Rodero
Pablo Lamata
Eigil Samset
Kristin Mcleod

Funding

Wellcome TrustWellcome Trust 209450/Z/17/Z
6 · The paper itself

Abstract

Deep learning can bring time savings and increased reproducibility to medical image analysis. However, acquiring training data is challenging due to the time-intensive nature of labeling and high inter-observer variability in annotations. Rather than labeling images, in this work we propose an alternative pipeline where images are generated from existing high-quality annotations using generative adversarial networks (GANs). Annotations are derived automatically from previously built anatomical models and are transformed into realistic synthetic ultrasound images with paired labels using a CycleGAN. We demonstrate the pipeline by generating synthetic 2D echocardiography images to compare with existing deep learning ultrasound segmentation datasets. A convolutional neural network is trained to segment the left ventricle and left atrium using only synthetic images. Networks trained with synthetic images were extensively tested on four different unseen datasets of real images with median Dice scores of 91, 90, 88, and 87 for left ventricle segmentation. These results match or are better than inter-observer results measured on real ultrasound datasets and are comparable to a network trained on a separate set of real images. Results demonstrate the images produced can effectively be used in place of real data for training. The proposed pipeline opens the door for automatic generation of training data for many tasks in medical imaging as the same process can be applied to other segmentation or landmark detection tasks in any modality. The source code and anatomical models are available to other researchers.

Indexed as

Image Processing, Computer-AssistedNeural Networks, ComputerEchocardiographyHumansReproducibility of ResultsUltrasonography

Identifiers

PMID33444134
PMCPMC8493532

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.