Evidence map›Paper›PMID 33444120›Full record

Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2021

Markers of branched-chain amino acid catabolism are not affected by exercise training in pregnant women with obesity.

Brittany R Allman, Beverly J Spray, Kelly E Mercer, Aline Andres, Elisabet Børsheim

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Brittany R AllmanArkansas Children's Nutrition Center, Little Rock, Arkansas.ORCID 0000-0002-0087-8847
Beverly J SprayArkansas Children's Research Institute, Little Rock, Arkansas.
Kelly E MercerArkansas Children's Nutrition Center, Little Rock, Arkansas.
Aline AndresArkansas Children's Nutrition Center, Little Rock, Arkansas.
Elisabet BørsheimArkansas Children's Nutrition Center, Little Rock, Arkansas.ORCID 0000-0002-7842-0625
Arkansas Children's Hospital · USArkansas Children's Nutrition Center · US

Funding

The Role of the Mitochondrion in the Metabolic Stress Response to Burn TraumaP20GM109096 · NIGMS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI SWINDLE, TAREN · 2016 to 2025
$20.7M
Phenotypic and metabolic characteristics in early childhood leading to obesityR01DK107516 · NIDDK · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI ANDRES, ALINE, BORSHEIM, ELISABET · 2016 to 2020
$1.6M
NIDDK NIH HHS R01 DK107516NIGMS NIH HHS COBRE 1P20GM109096-01A1NIGMS NIH HHS P20 GM109096
6 · The paper itself

Abstract

Despite the role of branched-chain amino acids (BCAAs) in physiological processes such as nutrient signaling and protein synthesis, there is ongoing debate about the link between circulating BCAAs and insulin resistance (IR) in various populations. In healthy women, IR mildly increases during pregnancy, whereas both BCAAs and markers of BCAA catabolism decrease, indicating that fetal growth is being prioritized. Exercise reduces IR in nonpregnant adults, but less is known about the effect of exercise during pregnancy in women with obesity on IR and BCAA breakdown. The aim of this study was to determine the effect of a moderate-intensity exercise intervention during pregnancy on maternal circulating BCAAs and markers of BCAA catabolism [short-chain acylcarnitines (ACs)], and their associations with IR. Healthy obese [

Indexed as

Insulin ResistancePregnant PeopleAdultAmino Acids, Branched-ChainExerciseFemaleHumansObesityPregnancyAmino Acids, Branched-ChainBCAAgestationinsulin resistanceobesityphysical activity

Identifiers

PMID33444120
PMCPMC7988795
OpenAlexW3118484557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.