Evidence map›Paper›PMID 33443719›Full record

Trial reportObesity surgery2021

Effects of Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 Supplementation on Nutritional and Metabolic Parameters in the Early Postoperative Period after Roux-en-Y Gastric Bypass: a Randomized, Double-Blind, Placebo-Controlled Trial.

Marília Rizzon Zaparolli Ramos, Lígia de Oliveira Carlos, Nathalia Ramori Farinha Wagner, Ingrid Felicidade, Magda Ramos da Cruz, Cesar Augusto Taconeli, Ricardo Fernandes, Alcides José Branco Filho, Antônio Carlos Ligocki Campos

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  13. [Research progress of probiotics regulating intestinal micro-ecological environment in obese patients after bariatric surgery].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marília Rizzon Zaparolli RamosUFPR, Curitiba, Brazil. mariliazaparolli@gmail.com.ORCID http://orcid.org/0000-0002-5112-6979
Lígia de Oliveira CarlosUFPR, Curitiba, Brazil.
Nathalia Ramori Farinha WagnerUFPR, Curitiba, Brazil.
Ingrid FelicidadeSchool of Medicine, Department of Pathology, São Paulo State University (UNESP), São Paulo, Brazil.
Magda Ramos da CruzNutrition Course of the Pontifical Catholic University of Paraná (PUCPR), Curitiba, Brazil.
Cesar Augusto TaconeliDepartment of Statistics, Federal University of Paraná, Curitiba, Brazil.
Ricardo FernandesFaculty of Health Sciences, Federal University of Grande Dourados, Dourados, Brazil.
Alcides José Branco FilhoSanta Casa de Misericórdia de Curitiba Hospital, Curitiba, Brazil.
Antônio Carlos Ligocki CamposPost-graduate Program in Clinical Surgery, Surgery Department, Federal University of Parana, Curitiba, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have suggested that Roux-en-Y gastric bypass (RYGB) causes changes in the intestinal microbiota composition and function due to anatomical and physiological modifications. The role of probiotic supplementation after bariatric procedures remains to be determined. PURPOSE: The aim of this study was to investigate the effects of Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 supplementation on nutritional and metabolic parameters after RYGB. MATERIALS AND

methodsThis is a randomized, double-blind, placebo-controlled clinical trial. Patients were assigned to receive either a probiotic supplement (FloraVantage®) or placebo for three consecutive months, beginning 7 days after surgery. Anthropometric and biochemical indexes were evaluated in the preoperative period and at the end of the study.

resultsFollowing RYGB, serum 25-OH vitamin D increased in both groups compared to baseline; however, this increase was significant only in the probiotic group (p = 0.004). Vitamin B

conclusionProbiotic supplementation after RYGB improves the vitamin and lipid profile.

Indexed as

Bifidobacterium animalisGastric BypassObesity, MorbidProbioticsDietary SupplementsDouble-Blind MethodHumansLactobacillus acidophilusPostoperative PeriodBariatric surgeryProbioticsRoux-en-Y gastric bypass

Identifiers

PMID33443719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.